UBXN10 and IFT80

Number of citations: 53 (PubMedID 26389662)
Data Source: BioGRID (pull down)

		UBXN10	IFT80
Name		UBX domain protein 10	intraflagellar transport 80
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Cilium Intraciliary Transport Particle B Cell Projection	Cytoplasm Centrosome Cytoskeleton Cilium Intraciliary Transport Particle B Ciliary Basal Body Cell Projection Ciliary Tip 9+0 Non-motile Cilium
	Molecular Function	Protein Binding Ubiquitin Binding	None
	Biological Process	Cell Projection Organization ERAD Pathway Cilium Assembly	Skeletal System Development Ossification Osteoblast Differentiation Endochondral Ossification Chondrocyte Differentiation Growth Plate Cartilage Development Growth Plate Cartilage Chondrocyte Differentiation Apoptotic Process Establishment Or Maintenance Of Cell Polarity Smoothened Signaling Pathway Canonical NF-kappaB Signal Transduction Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Tissue Development Gene Expression Proteasomal Protein Catabolic Process Negative Regulation Of Keratinocyte Proliferation Protein Ubiquitination Spinal Cord Development Osteoclast Differentiation Osteoblast Proliferation Multicellular Organism Growth Non-canonical Wnt Signaling Pathway Bone Mineralization Involved In Bone Maturation Intraciliary Anterograde Transport Odontogenesis Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Keratinocyte Proliferation Tooth Eruption Cilium Organization Stem Cell Differentiation Protein Stabilization Cartilage Development Limb Development Cilium Assembly Bone Development Bone Morphogenesis Articular Cartilage Development Odontoblast Differentiation Stem Cell Proliferation Receptor Localization To Non-motile Cilium Response To Inositol Non-motile Cilium Assembly Cartilage Homeostasis Negative Regulation Of Non-canonical Wnt Signaling Pathway
Pathways		None	Intraflagellar transport Intraflagellar transport
GWAS		Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471 )	Alanine aminotransferase levels ( 34315874 ) Aspartate aminotransferase levels ( 34315874 ) Bipolar disorder ( 31043756 ) LDL cholesterol ( 30275531 ) Liver enzyme levels (alanine transaminase) ( 33972514 ) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514 ) Malaria ( 31844061 )
Interacting Genes		13 interacting genes: APP CLUAP1 IFT46 IFT57 IFT70A IFT70B IFT80 LRRK2 PRMT6 TRAF3IP1 UBXN6 UNC13A VCP	2 interacting genes: PLXNA2 UBXN10
Entrez ID		127733	57560
HPRD ID		18255	13853
Ensembl ID		ENSG00000162543	ENSG00000068885
Uniprot IDs		Q96LJ8	Q9P2H3
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Intraciliary Transport Particle B Intraciliary Anterograde Transport Intraciliary Transport Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Ciliary Tip Microtubule-based Transport Establishment Of Localization In Cell Intracellular Transport Microtubule-based Movement Cellular Localization Microtubule-based Process Cell Projection Cell Projection Organization Cilium Assembly Cilium Organization Ciliary Basal Body Cilium Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Smoothened Signaling Pathway Cellular Component Assembly Plasma Membrane Bounded Cell Projection Organization Intraciliary Transport Particle B Binding Centrosome Ciliary Base Organelle Assembly Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Cellular Response To Manganese Ion Left/right Pattern Formation Response To Manganese Ion Microtubule Organizing Center Golgi-associated Vesicle Regulation Of Wnt Signaling Pathway Cellular Response To Catecholamine Stimulus Syntaxin-1 Binding Response To Catecholamine Negative Regulation Of Keratinocyte Proliferation Regulation Of Proteolysis Organelle Organization Keratinocyte Proliferation Regulation Of Ubiquitin-dependent Protein Catabolic Process Axonemal Microtubule Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Smoothened Signaling Pathway Positive Regulation Of ATP Metabolic Process Anatomical Structure Morphogenesis Terminal Bouton Cytoskeleton Endosome Transport Via Multivesicular Body Sorting Pathway	None