SLC44A3 and IMPA2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC44A3	IMPA2
Description		solute carrier family 44 member 3	inositol monophosphatase 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Cytoplasm Cytosol
	Molecular Function	Protein Binding Choline Transmembrane Transporter Activity Transmembrane Transporter Activity	Protein Binding Glucose-1-phosphatase Activity Inositol Monophosphate 1-phosphatase Activity Hydrolase Activity Protein Homodimerization Activity Metal Ion Binding Glycerol-2-phosphatase Activity Inositol Monophosphate 3-phosphatase Activity Inositol Monophosphate 4-phosphatase Activity Inositol Monophosphate Phosphatase Activity
	Biological Process	Phosphatidylcholine Biosynthetic Process Choline Transport Transmembrane Transport	Inositol Metabolic Process Inositol Biosynthetic Process Phosphate-containing Compound Metabolic Process Signal Transduction Response To Lithium Ion Phosphatidylinositol Phosphate Biosynthetic Process
Pathways		Synthesis of PC SLC-mediated bile acid transport	Synthesis of IP2, IP, and Ins in the cytosol
Drugs			Lithium cation Lithium citrate Lithium succinate Lithium carbonate
Diseases
GWAS		Computer vision syndrome ( 33941792) Haemorrhoidal disease ( 33888516) Metabolite levels (Dihydroxy docosatrienoic acid) ( 23934736) Myocardial infarction ( 33532862) Type 2 diabetes ( 22238593)	Diabetic peripheral neuropathy in type 2 diabetes ( 31127053) Hemoglobin ( 32888494) Obsessive-compulsive disorder or autism spectrum disorder ( 28641744) Stroke ( 17434096)
Interacting Genes		3 interacting genes: ABHD5 FHL3 IMPA2	5 interacting genes: CCT6A HERPUD1 SLC44A3 TNFRSF14 UBA3
Entrez ID		126969	3613
HPRD ID		14637	09329
Ensembl ID		ENSG00000143036	ENSG00000141401
Uniprot IDs		B4DTF4 E9PIC5 Q8N4M1	O14732
PDB IDs			2CZH 2CZI 2CZK 2DDK 2FVZ
Enriched GO Terms of Interacting Partners?		Glycerol-2-phosphatase Activity Glycerophospholipid Biosynthetic Process Inositol Monophosphate 4-phosphatase Activity Inositol Biosynthetic Process Inositol Monophosphate Phosphatase Activity Inositol Monophosphate 1-phosphatase Activity Glucose-1-phosphatase Activity Inositol Monophosphate 3-phosphatase Activity Negative Regulation Of Triglyceride Storage Lipase Activator Activity Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Inositol Metabolic Process Glycerolipid Metabolic Process Positive Regulation Of Triglyceride Catabolic Process Phospholipid Metabolic Process Lysophosphatidic Acid Acyltransferase Activity Response To Lithium Ion 1-acylglycerol-3-phosphate O-acyltransferase Activity Triacylglycerol Lipase Activity Lipid Biosynthetic Process Organophosphate Biosynthetic Process Negative Regulation Of Lipid Storage Positive Regulation Of Triglyceride Metabolic Process Positive Regulation Of Lipid Catabolic Process Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Carboxylic Ester Hydrolase Activity Regulation Of Triglyceride Metabolic Process Regulation Of Lipid Storage Phosphatidylinositol Phosphate Biosynthetic Process Regulation Of Lipid Catabolic Process	Positive Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Adaptive Immune Memory Response Endomitotic Cell Cycle NEDD8 Activating Enzyme Activity Lewy Body Core
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