CMTM3 and MRM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CMTM3	MRM1
Description		CKLF like MARVEL transmembrane domain containing 3	mitochondrial rRNA methyltransferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Membrane Cytoplasmic Vesicle Nuclear Membrane	Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Cytokine Activity Protein Binding	RNA Binding Protein Binding Methyltransferase Activity RNA Methyltransferase Activity RRNA (guanine) Methyltransferase Activity Transferase Activity RRNA (guanosine-2'-O-)-methyltransferase Activity
	Biological Process	Blastocyst Hatching Chemotaxis Signal Transduction Positive Regulation Of B Cell Receptor Signaling Pathway	RRNA Modification RRNA 2'-O-methylation RRNA Processing RNA Processing RRNA Methylation Methylation
Pathways			rRNA modification in the mitochondrion
Drugs
Diseases
GWAS			Body mass index ( 26426971) Carotid intima media thickness x smoking interaction ( 32117412)
Interacting Genes		30 interacting genes: APOA5 APP AQP6 ARL13B BLNK BTK CREB3L1 ELOVL4 GJB1 GPR35 HSD17B11 IKBIP IL10RA LEUTX LMNA LRRC59 MAPK1 MEST MOB1A MOB3C MRM1 RABAC1 REEP4 RETREG3 SLC10A1 SLC71A2 SPP1 STMN4 SYT2 VEZT	42 interacting genes: ADIPOQ AGTRAP AQP1 AQP2 AQP3 BRICD5 CCL4 CCL4L2 CDC42 CMTM3 CMTM5 CNIH1 COQ8A DNAJC30 EEF1A1 ERG28 ESRRG FKBP7 ITGAM KLRG1 LPAR3 MAL2 MESD MGST3 NRM NXPE3 RHBDD2 RNASE10 SELENOK SPX STATH STX7 SYP SYT3 TMEM11 TMEM243 TMEM42 TMEM97 TRARG1 TTPA VKORC1L1 VSTM1
Entrez ID		123920	79922
HPRD ID		16259	08656
Ensembl ID		ENSG00000140931	ENSG00000278619
Uniprot IDs		H3BUD5 J3KSR6 Q96MX0	Q6IN84
PDB IDs
Enriched GO Terms of Interacting Partners?			Polyol Transmembrane Transport Renal Water Transport Glycerol Transmembrane Transport Carbohydrate Transport Carbohydrate Transmembrane Transport Water Channel Activity Glycerol Transmembrane Transporter Activity Membrane Renal Water Homeostasis Cellular Response To Mercury Ion Water Transport Multicellular Organismal-level Water Homeostasis Water Transmembrane Transporter Activity Renal Water Absorption Fluid Transport Channel Activity Cytokine Activity Response To Mercury Ion Response To Bacterium Positive Regulation Of Monocyte Chemotactic Protein-1 Production
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