MRM1 and KLRG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MRM1	KLRG1
Description		mitochondrial rRNA methyltransferase 1	killer cell lectin like receptor G1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Plasma Membrane Membrane
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity RNA Methyltransferase Activity RRNA (guanine) Methyltransferase Activity Transferase Activity RRNA (guanosine-2'-O-)-methyltransferase Activity	Protein Binding Carbohydrate Binding Signaling Receptor Activity
	Biological Process	RRNA Modification RRNA 2'-O-methylation RRNA Processing RNA Processing RRNA Methylation Methylation	Immune System Process Inflammatory Response Cellular Defense Response Cell Surface Receptor Signaling Pathway Innate Immune Response
Pathways		rRNA modification in the mitochondrion	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Body mass index ( 26426971) Carotid intima media thickness x smoking interaction ( 32117412)	Appendicular lean mass ( 33097823) Refractive error ( 32231278) Sjögren's syndrome ( 28076899) Type 1 diabetes ( 34012112)
Interacting Genes		42 interacting genes: ADIPOQ AGTRAP AQP1 AQP2 AQP3 BRICD5 CCL4 CCL4L2 CDC42 CMTM3 CMTM5 CNIH1 COQ8A DNAJC30 EEF1A1 ERG28 ESRRG FKBP7 ITGAM KLRG1 LPAR3 MAL2 MESD MGST3 NRM NXPE3 RHBDD2 RNASE10 SELENOK SPX STATH STX7 SYP SYT3 TMEM11 TMEM243 TMEM42 TMEM97 TRARG1 TTPA VKORC1L1 VSTM1	7 interacting genes: ARL13B GPR42 GPX8 KLRC1 LEPROTL1 MRM1 SYNE4
Entrez ID		79922	10219
HPRD ID		08656	16076
Ensembl ID		ENSG00000278619	ENSG00000139187
Uniprot IDs		Q6IN84	Q96E93
PDB IDs			3FF7
Enriched GO Terms of Interacting Partners?		Polyol Transmembrane Transport Renal Water Transport Glycerol Transmembrane Transport Carbohydrate Transport Carbohydrate Transmembrane Transport Water Channel Activity Glycerol Transmembrane Transporter Activity Membrane Renal Water Homeostasis Cellular Response To Mercury Ion Water Transport Multicellular Organismal-level Water Homeostasis Water Transmembrane Transporter Activity Renal Water Absorption Fluid Transport Channel Activity Cytokine Activity Response To Mercury Ion Response To Bacterium Positive Regulation Of Monocyte Chemotactic Protein-1 Production	Establishment Of Apical/basal Cell Polarity Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Polarized Epithelial Cell Differentiation Establishment Of Epithelial Cell Apical/basal Polarity Establishment Of Epithelial Cell Polarity Telencephalon Cell Migration Establishment Or Maintenance Of Apical/basal Cell Polarity Forebrain Cell Migration Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Mitotic Cleavage Furrow Formation Inhibitory MHC Class Ib Receptor Activity Aortic Valve Formation Establishment Of Cell Polarity Positive Regulation Of Vascular Associated Smooth Muscle Contraction Endothelial Tube Lumen Extension Skeletal Muscle Satellite Cell Migration HLA-E Specific Inhibitory MHC Class Ib Receptor Activity RRNA (guanosine-2'-O-)-methyltransferase Activity Beta Selection Epithelial Tube Morphogenesis Natural Killer Cell Inhibitory Signaling Pathway CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation RRNA (guanine) Methyltransferase Activity RRNA 2'-O-methylation Receptor Localization To Non-motile Cilium Bone Trabecula Morphogenesis Formation Of Radial Glial Scaffolds Apolipoprotein A-I-mediated Signaling Pathway Establishment Or Maintenance Of Cell Polarity Roundabout Signaling Pathway Regulation Of Systemic Arterial Blood Pressure By Endothelin Forebrain Radial Glial Cell Differentiation MHC Class Ib Receptor Activity Positive Regulation Of Lipase Activity Cleavage Furrow Formation Cell Morphogenesis Apical Junction Assembly Negative Regulation Of Oxidative Phosphorylation Regulation Of Modification Of Postsynaptic Actin Cytoskeleton MHC Class I Protein Complex Binding Protein Localization To Ciliary Membrane Interneuron Migration From The Subpallium To The Cortex Neural Tube Patterning Negative Regulation Of Cell Size Ossification Involved In Bone Maturation Negative Regulation Of Cellular Respiration Immune Response-inhibiting Cell Surface Receptor Signaling Pathway Protein Antigen Binding
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