MRM1 and CNIH1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MRM1	CNIH1
Description		mitochondrial rRNA methyltransferase 1	cornichon family member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus ER To Golgi Transport Vesicle Membrane Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity RNA Methyltransferase Activity RRNA (guanine) Methyltransferase Activity Transferase Activity RRNA (guanosine-2'-O-)-methyltransferase Activity	Signaling Receptor Binding Protein Binding
	Biological Process	RRNA Modification RRNA 2'-O-methylation RRNA Processing RNA Processing RRNA Methylation Methylation	Immune Response Signal Transduction Vesicle-mediated Transport
Pathways		rRNA modification in the mitochondrion	COPII-mediated vesicle transport Cargo concentration in the ER
Drugs
Diseases
GWAS		Body mass index ( 26426971) Carotid intima media thickness x smoking interaction ( 32117412)	Monobrow thickness ( 26926045)
Interacting Genes		42 interacting genes: ADIPOQ AGTRAP AQP1 AQP2 AQP3 BRICD5 CCL4 CCL4L2 CDC42 CMTM3 CMTM5 CNIH1 COQ8A DNAJC30 EEF1A1 ERG28 ESRRG FKBP7 ITGAM KLRG1 LPAR3 MAL2 MESD MGST3 NRM NXPE3 RHBDD2 RNASE10 SELENOK SPX STATH STX7 SYP SYT3 TMEM11 TMEM243 TMEM42 TMEM97 TRARG1 TTPA VKORC1L1 VSTM1	32 interacting genes: AQP6 BIK CD53 CD79A CLDN7 CPLX4 CYB5R3 ERGIC3 EVI2B FAM209A FCER1G FFAR2 FKBP7 GPR152 GPX8 HTR2C LEUTX LRRC59 MCEMP1 MFF MRM1 OPRM1 RNF24 SAR1A SHISA4 SLC10A6 SLC18A1 SLC22A23 SLC35H1 SMIM3 TMEM52B TSC1
Entrez ID		79922	10175
HPRD ID		08656	16730
Ensembl ID		ENSG00000278619	ENSG00000100528
Uniprot IDs		Q6IN84	B2R4P1 O95406
PDB IDs
Enriched GO Terms of Interacting Partners?		Polyol Transmembrane Transport Renal Water Transport Glycerol Transmembrane Transport Carbohydrate Transport Carbohydrate Transmembrane Transport Water Channel Activity Glycerol Transmembrane Transporter Activity Membrane Renal Water Homeostasis Cellular Response To Mercury Ion Water Transport Multicellular Organismal-level Water Homeostasis Water Transmembrane Transporter Activity Renal Water Absorption Fluid Transport Channel Activity Cytokine Activity Response To Mercury Ion Response To Bacterium Positive Regulation Of Monocyte Chemotactic Protein-1 Production	Membrane
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