CMTM3 and MOB3C

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		CMTM3	MOB3C
Description		CKLF like MARVEL transmembrane domain containing 3	MOB kinase activator 3C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Membrane Cytoplasmic Vesicle Nuclear Membrane	Nucleus Cytoplasm
	Molecular Function	Cytokine Activity Protein Binding	Protein Binding Protein Kinase Activator Activity Metal Ion Binding
	Biological Process	Blastocyst Hatching Chemotaxis Signal Transduction Positive Regulation Of B Cell Receptor Signaling Pathway	Signal Transduction
Pathways
Drugs
Diseases
GWAS			Chronic kidney disease ( 30226566) Hypertension ( 30226566)
Interacting Genes		30 interacting genes: APOA5 APP AQP6 ARL13B BLNK BTK CREB3L1 ELOVL4 GJB1 GPR35 HSD17B11 IKBIP IL10RA LEUTX LMNA LRRC59 MAPK1 MEST MOB1A MOB3C MRM1 RABAC1 REEP4 RETREG3 SLC10A1 SLC71A2 SPP1 STMN4 SYT2 VEZT	18 interacting genes: APP CMTM3 FAM118A FBXO7 IKZF4 KANK2 KRT40 LATS1 LATS2 NT5C2 PCYT1A PICK1 PTPN21 SIAH1 TDO2 TFCP2 TNIP1 ZBTB10
Entrez ID		123920	148932
HPRD ID		16259	17584
Ensembl ID		ENSG00000140931	ENSG00000142961
Uniprot IDs		H3BUD5 J3KSR6 Q96MX0	Q70IA8 X6R3L3
PDB IDs
Enriched GO Terms of Interacting Partners?			Inner Cell Mass Cell Fate Commitment Inner Cell Mass Cellular Morphogenesis Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Cyclin-dependent Protein Kinase Activity Amide Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signaling Amyloid Fibril Formation Regulation Of Protein Localization To Nucleus Cytosol Positive Regulation Of Receptor Internalization Negative Regulation Of Cell Communication Identical Protein Binding Phosphate-containing Compound Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Hippo Signaling Negative Regulation Of Cell Cycle Negative Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of NLRP3 Inflammasome Complex Assembly Positive Regulation Of Hippo Signaling Amyloid-beta Complex Protein Homooligomerization Growth Cone Lamellipodium Neuron Projection Organization Negative Regulation Of Wnt Signaling Pathway Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Supramolecular Fiber Organization Positive Regulation Of Toll Signaling Pathway Protein Modification Process L-tryptophan Catabolic Process To Acetyl-CoA Regulation Of Hippo Signaling Regulation Of Intracellular Estrogen Receptor Signaling Pathway Nucleoside Phosphotransferase Activity GMP Catabolic Process To Guanine Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Regulation Of NLRP3 Inflammasome Complex Assembly Protein Metabolic Process Negative Regulation Of Protein Localization Positive Regulation Of Receptor-mediated Endocytosis Acetylcholine Receptor Activator Activity Positive Regulation Of Apoptotic Process Lipoprotein Particle Positive Regulation Of Protein Import Glial Cell Development
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