COASY and KIAA1958

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		COASY	KIAA1958
Description		Coenzyme A synthase	KIAA1958
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Mitochondrial Matrix Extracellular Exosome
	Molecular Function	Nucleotide Binding Catalytic Activity Dephospho-CoA Kinase Activity Pantetheine-phosphate Adenylyltransferase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Nucleotidyltransferase Activity	Protein Binding
	Biological Process	Coenzyme A Biosynthetic Process
Pathways		Coenzyme A biosynthesis
Drugs
Diseases
GWAS		Medication use (drugs used in diabetes) ( 31015401) Metabolic syndrome ( 31589552)	Caudate nucleus volume ( 31530798) Cobalt levels ( 26025379) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397) Self-reported childhood asthma in adult smokers ( 30373671)
Interacting Genes		12 interacting genes: APP BTK CFTR CNTROB KIAA1958 KRT20 LYN PJA1 RPS6KB1 RPS6KB2 SRC SYK	13 interacting genes: AQP1 CEP19 COASY FAM124B GABARAPL2 LMO4 MCRS1 RWDD2B SOCS3 STAC TCEA2 TCEANC THAP12
Entrez ID		80347	158405
HPRD ID		13080	11173
Ensembl ID		ENSG00000068120	ENSG00000165185
Uniprot IDs		Q13057	Q8N8K9
PDB IDs
Enriched GO Terms of Interacting Partners?		Signaling Receptor Activator Activity Peptidyl-tyrosine Phosphorylation Non-membrane Spanning Protein Tyrosine Kinase Activity Fc Receptor Signaling Pathway TORC1 Signaling Phospholipase Binding Stimulatory C-type Lectin Receptor Signaling Pathway Cellular Response To Lectin TOR Signaling Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-epsilon Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Ephrin Receptor Binding Protein Kinase Activity Negative Regulation Of Inflammatory Response To Antigenic Stimulus Cellular Response To Oxygen-containing Compound Regulation Of Vesicle-mediated Transport Fc-gamma Receptor Signaling Pathway Protein Tyrosine Kinase Activity Cellular Response To Molecule Of Fungal Origin Integrin Binding Kinase Activity Histamine Secretion By Mast Cell Protein Phosphorylation Response To Molecule Of Fungal Origin Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Pattern Recognition Receptor Signaling Pathway Cellular Developmental Process Phosphorylation B Cell Receptor Signaling Pathway Positive Regulation Of Cell Activation Innate Immune Response-activating Signaling Pathway Histamine Secretion Regulation Of Inflammatory Response Regulation Of Innate Immune Response Glial Cell Development Activation Of Innate Immune Response Positive Regulation Of TORC1 Signaling Negative Regulation Of TORC1 Signaling Membrane Raft Response To Lipid Positive Regulation Of Defense Response Histamine Transport Cellular Response To Lipid Positive Regulation Of Protein Metabolic Process Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Scaffold Protein Binding Positive Regulation Of Developmental Process Phospholipase Activator Activity
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