COASY and KRT20

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COASY	KRT20
Description		Coenzyme A synthase	keratin 20
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Mitochondrial Matrix Extracellular Exosome	Cytoplasm Cytosol Cytoskeleton Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton
	Molecular Function	Nucleotide Binding Catalytic Activity Dephospho-CoA Kinase Activity Pantetheine-phosphate Adenylyltransferase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Nucleotidyltransferase Activity	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Coenzyme A Biosynthetic Process	Morphogenesis Of An Epithelium Apoptotic Process Cellular Response To Starvation Epithelial Cell Differentiation Intermediate Filament Organization Regulation Of Protein Secretion
Pathways		Coenzyme A biosynthesis	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Medication use (drugs used in diabetes) ( 31015401) Metabolic syndrome ( 31589552)	Height ( 19893584)
Interacting Genes		12 interacting genes: APP BTK CFTR CNTROB KIAA1958 KRT20 LYN PJA1 RPS6KB1 RPS6KB2 SRC SYK	45 interacting genes: ABI2 AMOTL2 ANKRD36BP1 BBLN BCAS2 CCDC196 CCDC85B COASY CYSRT1 DES EIF4E2 EXOC8 FXR2 KRT13 KRT15 KRT24 KRT27 KRT3 KRT31 KRT34 KRT40 KRT72 KRT75 KRT80 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP6-3 NOTCH2NLA NUP62 PIK3R2 PLEKHA5 PPP1R13B PRC1 PRPH SNAPIN TFIP11 TXLNA USHBP1 VIM WASHC1 ZC2HC1C ZC3H14
Entrez ID		80347	54474
HPRD ID		13080	12193
Ensembl ID		ENSG00000068120	ENSG00000171431
Uniprot IDs		Q13057	P35900
PDB IDs
Enriched GO Terms of Interacting Partners?		Signaling Receptor Activator Activity Peptidyl-tyrosine Phosphorylation Non-membrane Spanning Protein Tyrosine Kinase Activity Fc Receptor Signaling Pathway TORC1 Signaling Phospholipase Binding Stimulatory C-type Lectin Receptor Signaling Pathway Cellular Response To Lectin TOR Signaling Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-epsilon Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Ephrin Receptor Binding Protein Kinase Activity Negative Regulation Of Inflammatory Response To Antigenic Stimulus Cellular Response To Oxygen-containing Compound Regulation Of Vesicle-mediated Transport Fc-gamma Receptor Signaling Pathway Protein Tyrosine Kinase Activity Cellular Response To Molecule Of Fungal Origin Integrin Binding Kinase Activity Histamine Secretion By Mast Cell Protein Phosphorylation Response To Molecule Of Fungal Origin Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Pattern Recognition Receptor Signaling Pathway Cellular Developmental Process Phosphorylation B Cell Receptor Signaling Pathway Positive Regulation Of Cell Activation Innate Immune Response-activating Signaling Pathway Histamine Secretion Regulation Of Inflammatory Response Regulation Of Innate Immune Response Glial Cell Development Activation Of Innate Immune Response Positive Regulation Of TORC1 Signaling Negative Regulation Of TORC1 Signaling Membrane Raft Response To Lipid Positive Regulation Of Defense Response Histamine Transport Cellular Response To Lipid Positive Regulation Of Protein Metabolic Process Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Scaffold Protein Binding Positive Regulation Of Developmental Process Phospholipase Activator Activity	Intermediate Filament Keratin Filament Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Supramolecular Fiber Organization Cytoskeleton Organization Structural Molecule Activity Organelle Organization Cytosol Cytoskeleton Keratinization Structural Constituent Of Cytoskeleton Intermediate Filament Cytoskeleton Epithelial Cell Differentiation Morphogenesis Of An Epithelium Tissue Morphogenesis Protein Binding Epidermis Development Cell Differentiation Developmental Process Exocyst
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