COASY and KRT20

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COASY	KRT20
Gene Name		CoA synthase	keratin 20, type I
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Mitochondrial Matrix Extracellular Vesicular Exosome	Cytoplasm Intermediate Filament
	Molecular Function	Dephospho-CoA Kinase Activity Pantetheine-phosphate Adenylyltransferase Activity Protein Binding ATP Binding	Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Coenzyme Biosynthetic Process Coenzyme A Biosynthetic Process Pantothenate Metabolic Process Phosphorylation Small Molecule Metabolic Process	Apoptotic Process Cellular Response To Stress Intermediate Filament Organization Regulation Of Protein Secretion
Pathways		Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Vitamin B5 (pantothenate) metabolism Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Coenzyme A biosynthesis Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS			Height ( 19893584)
Protein-Protein Interactions		6 interactors: APP CNTROB KIAA1958 KRT20 RPS6KB1 RPS6KB2	27 interactors: ABI2 AMOTL2 ANKRD36BP1 C9orf16 CCDC85B COASY EIF4E2 EXOC8 FXR2 KRT13 KRT15 KRT40 KRT80 KRTAP10-7 KRTAP10-8 KRTAP10-9 NOTCH2NL NUP62 PIK3R2 PLEKHA5 PRC1 TFIP11 TXLNA USHBP1 VIM ZC2HC1C ZC3H14
Entrez ID		80347	54474
HPRD ID		13080	12193
Ensembl ID		ENSG00000068120	ENSG00000171431
Uniprot IDs		Q13057	P35900
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Translational Initiation Regulation Of Translation Protein Kinase B Signaling Posttranscriptional Regulation Of Gene Expression Regulation Of Translational Initiation Positive Regulation Of Translation Positive Regulation Of Mitotic Cell Cycle Phosphatidylinositol-mediated Signaling Synaptic Growth At Neuromuscular Junction Positive Regulation Of Skeletal Muscle Tissue Growth Collateral Sprouting In Absence Of Injury Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Skeletal Muscle Atrophy Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Striated Muscle Atrophy Response To Leucine Learning Or Memory Positive Regulation Of Protein Metabolic Process Axon Choice Point Recognition Muscle Atrophy Positive Regulation Of Cell Cycle Regulation Of Developmental Growth Cognition Mitotic Cytokinetic Process Protein Phosphorylation Skeletal Muscle Adaptation Neuron Remodeling Response To Stress Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Mitotic Cell Cycle Centrosome Separation Centriole Replication Single-organism Behavior Intermediate Filament Organization Cellular Copper Ion Homeostasis Phosphorylation TOR Signaling Copper Ion Homeostasis Suckling Behavior Regulation Of Cellular Protein Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Tagcloud ?		aceruloplasminemia atp13a2 autophagosome avenues c19orf12 c2orf37 ceruloplasmin comprehension connection description eventually fa2h faster ftl hope infer iron let metabolism nbia neurodegenerative neuroferritinopathy nucleolar pank2 pave perturbation pla2g6 underlining wdr45	17q 17q12 amplicon amplification amplifications amplified anthracycline besides ccr7 concerning gast grb7 heterogeneity heterogeneous igfpb4 iia implications krt19 locus med1 pitfalls presents rara stard3 subgroup thra top2a topoisomerase variations
Tagcloud (Difference) ?		aceruloplasminemia atp13a2 autophagosome avenues c19orf12 c2orf37 ceruloplasmin comprehension connection description eventually fa2h faster ftl hope infer iron let metabolism nbia neurodegenerative neuroferritinopathy nucleolar pank2 pave perturbation pla2g6 underlining wdr45	17q 17q12 amplicon amplification amplifications amplified anthracycline besides ccr7 concerning gast grb7 heterogeneity heterogeneous igfpb4 iia implications krt19 locus med1 pitfalls presents rara stard3 subgroup thra top2a topoisomerase variations
Tagcloud (Intersection) ?