ARL11 and TRIP13

Number of citations of the paper that reports this interaction (PubMedID 19060904)
32

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ARL11	TRIP13
Description		ARF like GTPase 11	thyroid hormone receptor interactor 13
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane	Male Germ Cell Nucleus Nucleus Chromosome
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding	Nucleotide Binding Transcription Coregulator Activity Protein Binding ATP Binding ATP Hydrolysis Activity Identical Protein Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Intracellular Protein Transport Vesicle-mediated Transport	Oocyte Maturation Double-strand Break Repair Transcription By RNA Polymerase II Mitotic Spindle Assembly Checkpoint Signaling Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Cell Differentiation Oogenesis Meiotic Cell Cycle Meiotic Recombination Checkpoint Signaling
Pathways
Drugs
Diseases
GWAS		Multiple sclerosis ( 23412934) Refractive error ( 32231278) Systemic lupus erythematosus ( 33536424)	Pancreatic cancer ( 25086665)
Interacting Genes		4 interacting genes: JAK2 PLD1 SMARCB1 TRIP13	113 interacting genes: ACTMAP ADAM15 AMDHD2 ANKRD10 ARL11 ARSA ASB13 BKGD BUB1B C4orf33 CARD14 CD99 CDC20 CDIN1 CEP170B CFP CLIP4 COMT CRMP1 CRYBA2 CYB5R2 DCTN3 DDAH2 DIP2A DPYSL4 DTX2 EEF2KMT FBLN5 FBXO8 FILNC1 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 IGFN1 IL2RB INCA1 INTS11 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1 MAD2L1BP MBLAC1 MEAK7 METTL15 MGAT5B MORN3 MPPED2 MVP MYEOV NIF3L1 NME4 NTAQ1 PARP11 PAX9 PBLD PCMTD2 PCSK5 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 POLR2L PPP2CA PRKAA2 PRKN PRR13 PSMB8 QARS1 RBPMS RHOXF2 RNF4 SCP2 SDCBP SEC24A SELENBP1 SEMA3B SEMA4G SHARPIN SIGLEC5 SMUG1 SPMIP9 SPRYD7 SSC4D STAMBP STAMBPL1 SUMO2 TENT5B THRB TINAGL1 TNRC6A TPT1 UBE2I VDR VENTX ZMYM5 ZNF34 ZNF655
Entrez ID		115761	9319
HPRD ID		12484	05145
Ensembl ID		ENSG00000152213	ENSG00000071539
Uniprot IDs		Q969Q4	Q15645
PDB IDs			5VQ9 5VQA 5WC2 6F0X 6LK0 7L9P
Enriched GO Terms of Interacting Partners?		Histone H3Y41 Kinase Activity Nuclear Receptor-mediated Mineralocorticoid Signaling Pathway Symbiont-induced Defense-related Programmed Cell Death Interleukin-35-mediated Signaling Pathway Regulation Of Sister Chromatid Segregation Regulation Of Mitotic Metaphase/anaphase Transition Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Regulation Of Postsynapse To Nucleus Signaling Pathway Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Organelle Subcompartment Regulation Of Chromosome Segregation Nucleobase-containing Compound Biosynthetic Process Interleukin-12 Receptor Complex Positive Regulation Of Skeletal Muscle Cell Proliferation Positive Regulation Of Growth Hormone Receptor Signaling Pathway Positive Regulation Of Glucose Mediated Signaling Pathway Germ Cell Nucleus Meiotic Recombination Checkpoint Signaling Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway Response To Interleukin-12 Interleukin-23 Receptor Complex Granulocyte Macrophage Colony-stimulating Factor Receptor Complex Activation Of Janus Kinase Activity Regulation Of Glucose Mediated Signaling Pathway Endomembrane System Type 1 Angiotensin Receptor Binding Thrombopoietin-mediated Signaling Pathway Positive Regulation Of Gene Expression Negative Regulation Of Growth Hormone Receptor Signaling Pathway Interleukin-12-mediated Signaling Pathway Positive Regulation Of NK T Cell Activation RNA Metabolic Process Erythropoietin-mediated Signaling Pathway Interleukin-3-mediated Signaling Pathway Macromolecule Biosynthetic Process Negative Regulation Of 3'-UTR-mediated MRNA Stabilization Post-embryonic Hemopoiesis Positive Regulation Of Lymphocyte Activation Interleukin-23-mediated Signaling Pathway Positive Regulation Of Cell-cell Adhesion Growth Hormone Receptor Binding Cellular Response To Interleukin-3 Interleukin-5-mediated Signaling Pathway Interleukin-12 Receptor Binding Positive Regulation Of T Cell Activation Positive Regulation Of Leukocyte Cell-cell Adhesion Nuclear Receptor-mediated Corticosteroid Signaling Pathway Extrinsic Component Of Plasma Membrane Positive Regulation Of NK T Cell Proliferation Transcription By RNA Polymerase II	Protein Binding Mitotic Checkpoint Complex Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds Protein K6-linked Ubiquitination Intermediate Filament
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