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MARCH3 and UBE2D2
Number of citations of the paper that reports this interaction (PMID
19549727
)
40
Data Source:
BioGRID
(two hybrid)
MARCH3
UBE2D2
Gene Name
membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
ubiquitin-conjugating enzyme E2D 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Lysosome
Endosome
Integral Component Of Membrane
Cytoplasmic Vesicle Membrane
Early Endosome Membrane
Ubiquitin Ligase Complex
Nucleoplasm
Cytosol
Protein Complex
Extracellular Vesicular Exosome
Molecular Function
Zinc Ion Binding
Ligase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Endocytosis
Protein Ubiquitination
Protein Polyubiquitination
Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Cellular Protein Modification Process
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Innate Immune Response
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Protein K48-linked Ubiquitination
Cellular Response To Hypoxia
Pathways
Cellular response to hypoxia
Regulation of Hypoxia-inducible Factor (HIF) by oxygen
Antigen processing: Ubiquitination & Proteasome degradation
Negative regulators of RIG-I/MDA5 signaling
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
IKK complex recruitment mediated by RIP1
TRIF-mediated TLR3/TLR4 signaling
MyD88-independent cascade
Activated TLR4 signalling
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Toll-Like Receptors Cascades
Toll Like Receptor 4 (TLR4) Cascade
Toll Like Receptor 3 (TLR3) Cascade
Class I MHC mediated antigen processing & presentation
Innate Immune System
Adaptive Immune System
Drugs
Diseases
GWAS
Immune reponse to smallpox (secreted IFN-alpha) (
22610502
)
Protein-Protein Interactions
8 interactors:
APP
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2K
UBE2W
167 interactors:
AMFR
ANAPC11
ARIH2
BARD1
BFAR
BIRC2
BIRC3
BIRC7
BIRC8
BRCA1
BTRC
CADPS2
CBL
CBLC
CCNB1
CDKN1B
CHFR
CNOT4
CUL3
DDX58
DTX1
DTX3
DTX3L
DZIP3
EPS15
F12
FBXL3
FBXO2
FBXO4
FBXO7
FBXW2
FZR1
HERC4
HUWE1
ITCH
KCMF1
LNX1
LRSAM1
LTN1
MAP3K1
MAPT
MARCH3
MARCH5
MARCH6
MARCH7
MDM2
MDM4
MGRN1
MIB1
MID1
MKRN3
MUL1
MYLIP
NEDD4
NEDD4L
NFKBIA
NHLRC1
NSMCE1
OTUB1
PARK2
PDZRN3
PELI1
PJA1
PJA2
POLL
POLM
QSOX1
RAF1
RAG1
RBX1
RCHY1
RELA
RFFL
RFWD2
RFWD3
RING1
RLIM
RMND5B
RNF10
RNF103
RNF11
RNF111
RNF114
RNF115
RNF122
RNF125
RNF126
RNF13
RNF130
RNF135
RNF138
RNF14
RNF146
RNF150
RNF151
RNF165
RNF166
RNF167
RNF181
RNF185
RNF186
RNF2
RNF25
RNF26
RNF34
RNF38
RNF4
RNF43
RNF5
RNF7
RSPRY1
SIAH1
SIAH2
SOCS6
STAM2
STK11
STUB1
SYVN1
TOPORS
TRAF6
TRAF7
TRAIP
TRIM10
TRIM13
TRIM17
TRIM2
TRIM21
TRIM23
TRIM25
TRIM26
TRIM27
TRIM28
TRIM31
TRIM32
TRIM35
TRIM36
TRIM37
TRIM38
TRIM39
TRIM41
TRIM43
TRIM45
TRIM5
TRIM50
TRIM55
TRIM63
TRIM7
TRIM8
TTC3
UBA1
UBA6
UBASH3B
UBC
UBE3A
UBE4A
UBE4B
UBOX5
UBR5
UFM1
UHRF2
VPRBP
VPS18
WWP2
XIAP
ZNRF1
ZNRF2
ZNRF4
Entrez ID
115123
7322
HPRD ID
14362
04268
Ensembl ID
ENSG00000173926
ENSG00000131508
Uniprot IDs
Q86UD3
P62837
PDB IDs
1UR6
1W4U
2C4O
2CLW
2ESK
2ESO
2ESP
2ESQ
3A33
3JVZ
3JW0
3L1Y
3TGD
3ZNI
4A49
4A4B
4A4C
4AUQ
4DDG
Enriched GO Terms of Interacting Partners
?
Protein K48-linked Ubiquitination
Protein Polyubiquitination
Protein K11-linked Ubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Cellular Protein Modification Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Protein Monoubiquitination
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Protein Metabolic Process
ISG15-protein Conjugation
Cellular Macromolecule Catabolic Process
Protein Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle Phase Transition
Cellular Response To Stress
Protein K63-linked Ubiquitination
Proteolysis
Catabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of DNA-templated Transcription In Response To Stress
Positive Regulation Of Cell Cycle Phase Transition
TRIF-dependent Toll-like Receptor Signaling Pathway
Response To Stress
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Regulation Of Mitotic Cell Cycle
Toll-like Receptor 4 Signaling Pathway
Regulation Of Cell Cycle Process
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Toll-like Receptor Signaling Pathway
Cellular Response To Oxygen Levels
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Mitotic Cell Cycle
Cellular Response To Stimulus
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Collateral Sprouting In Absence Of Injury
Activation Of Innate Immune Response
Regulation Of Proteolysis
Cellular Metabolic Process
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Protein Polyubiquitination
Protein Metabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein Autoubiquitination
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Proteolysis
Cellular Metabolic Process
Catabolic Process
Proteasomal Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Regulation Of Protein Ubiquitination
Protein Monoubiquitination
Metabolic Process
Protein K63-linked Ubiquitination
Regulation Of Protein Metabolic Process
Negative Regulation Of Viral Release From Host Cell
Regulation Of Viral Release From Host Cell
Positive Regulation Of Protein Ubiquitination
Regulation Of Cellular Protein Metabolic Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Response To Stress
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Response To Stress
Positive Regulation Of Protein Catabolic Process
Regulation Of Signal Transduction
Innate Immune Response
Regulation Of Protein Catabolic Process
Cellular Process
Apoptotic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Programmed Cell Death
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Viral Process
Cell Death
Regulation Of Proteolysis
Death
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Viral Entry Into Host Cell
Regulation Of Signaling
Tagcloud
?
actb
aging
analysed
comprehensive
cows
deltact
differed
dominant
durations
eif2b2
follicle
follicles
follicular
fsh
gapdh
genorm
geometric
granulosa
maternal
normfinder
preovulatory
programs
ranking
reference
reffinder
rnf20
sf3a1
suitable
threshold
Tagcloud (Difference)
?
actb
aging
analysed
comprehensive
cows
deltact
differed
dominant
durations
eif2b2
follicle
follicles
follicular
fsh
gapdh
genorm
geometric
granulosa
maternal
normfinder
preovulatory
programs
ranking
reference
reffinder
rnf20
sf3a1
suitable
threshold
Tagcloud (Intersection)
?