MARCH3

Gene Name		membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Endosome Integral Component Of Membrane Cytoplasmic Vesicle Membrane Early Endosome Membrane
	Molecular Function	Zinc Ion Binding Ligase Activity
	Biological Process	Endocytosis Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		8 interactors: APP UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2K UBE2W
Entrez ID		115123
HPRD ID		14362
Ensembl ID		ENSG00000173926
Uniprot IDs		Q86UD3
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Protein K11-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Monoubiquitination Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Metabolic Process ISG15-protein Conjugation Cellular Macromolecule Catabolic Process Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Cellular Response To Stress Protein K63-linked Ubiquitination Proteolysis Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Cell Cycle Phase Transition TRIF-dependent Toll-like Receptor Signaling Pathway Response To Stress MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Mitotic Cell Cycle Toll-like Receptor 4 Signaling Pathway Regulation Of Cell Cycle Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Synaptic Growth At Neuromuscular Junction Positive Regulation Of Mitotic Cell Cycle Cellular Response To Stimulus Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Collateral Sprouting In Absence Of Injury Activation Of Innate Immune Response Regulation Of Proteolysis Cellular Metabolic Process
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