CHRNB4 and CHRNA2

  • Number of citations of the paper that reports this interaction (PubMedID 8906617)
  • 0
  • Data Source:
  • HPRD (in vitro, in vivo)

CHRNB4

CHRNA2

Description cholinergic receptor nicotinic beta 4 subunit cholinergic receptor nicotinic alpha 2 subunit
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Attention function in attention deficit hyperactive disorder ( 26174813)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Benign childhood epilepsy with centro-temporal spikes ( 32580138)
  • BMI (smoking interaction) ( 28443625)
  • BMI in smokers ( 28443625)
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Chronic obstructive pulmonary disease x ever smoker interaction (1df) ( 33106845)
  • Coronary artery disease ( 33020668 32469254)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Exhaled carbon monoxide levels ( 25072098)
  • Gut microbiota relative abundance (Parabacteroides) ( 33208821)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 18385738 28604730 18780872 31577861)
  • Lung cancer in ever smokers ( 28604730)
  • Nicotine dependence ( 18385739 26440539)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
  • Refractive error ( 32231278)
  • Schizophrenia ( 29483656 25056061)
  • Small cell lung carcinoma ( 28604730)
  • Smoking status (heavy vs light) ( 28520984)
  • Squamous cell lung carcinoma ( 28604730)
  • Sudden cardiac arrest ( 21658281)
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Cannabis use disorder ( 31209380 33096046)
  • Lung cancer ( 28604730)
  • Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901)
  • Schizophrenia ( 29483656)
  • Smoking status (current vs mixed) ( 33082346)
  • Smoking status (current vs never) ( 33082346)
Interacting Genes 6 interacting genes: CHRNA2 CHRNA3 CHRNA4 CHRNA5 MEOX2 UBQLN1 2 interacting genes: CHRNB2 CHRNB4
Entrez ID 1143 1135
HPRD ID 00337 00332
Ensembl ID ENSG00000117971 ENSG00000120903
Uniprot IDs P30926 Q15822
PDB IDs 6PV7 6PV8 5FJV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?