CHRNA2

Gene Name		cholinergic receptor, nicotinic, alpha 2 (neuronal)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Acetylcholine-gated Channel Complex Integral Component Of Membrane Cell Junction Postsynaptic Membrane
	Molecular Function	Acetylcholine-activated Cation-selective Channel Activity Drug Binding Acetylcholine Receptor Activity Acetylcholine Binding
	Biological Process	Ion Transport Cation Transport Signal Transduction Synaptic Transmission Protein Heterooligomerization Cation Transmembrane Transport
Pathways		Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Acetylcholine Binding And Downstream Events Activation of Nicotinic Acetylcholine Receptors Postsynaptic nicotinic acetylcholine receptors Presynaptic nicotinic acetylcholine receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Highly calcium permeable nicotinic acetylcholine receptors Transmission across Chemical Synapses
Drugs		Nicotine Carbachol Metocurine Iodide Gallamine Triethiodide Dextromethorphan Cisatracurium Besylate Mecamylamine Galantamine Procaine Rocuronium Atracurium Biperiden Doxacurium chloride Tubocurarine Mivacurium Decamethonium Metocurine Pancuronium Pipecuronium Vecuronium
Diseases
GWAS
Protein-protein Interactions		2 interactors: CHRNB2 CHRNB4
Entrez ID		1135
HPRD ID		00332
Ensembl ID		ENSG00000120903
Uniprot IDs		B4DK19 J3KMY9 Q15822
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Transmission Involved In Micturition Micturition Behavioral Response To Nicotine Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Response To Nicotine Excretion Smooth Muscle Contraction Action Potential Renal System Process Response To Alkaloid Adult Behavior Lateral Geniculate Nucleus Development Muscle Contraction Locomotory Behavior Muscle System Process Regulation Of Membrane Potential Regulation Of Synaptic Transmission Negative Regulation Of Action Potential Single-organism Behavior Regulation Of Circadian Sleep/wake Cycle, REM Sleep Positive Regulation Of Dopamine Secretion Conditioned Taste Aversion Synaptic Transmission Behavior Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Positive Regulation Of Synaptic Transmission, Dopaminergic Vestibulocochlear Nerve Development Regulation Of Secretion Optic Nerve Morphogenesis Positive Regulation Of Catecholamine Secretion Optic Nerve Development Thalamus Development Response To Organonitrogen Compound Response To Organic Cyclic Compound Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Synaptic Transmission, Dopaminergic Cell-cell Signaling Cation Transmembrane Transport Regulation Of Dopamine Metabolic Process Regulation Of Dopamine Secretion Regulation Of Cellular Localization Cation Transport Ion Transmembrane Transport Positive Regulation Of B Cell Proliferation Central Nervous System Projection Neuron Axonogenesis Social Behavior Response To Cocaine Regulation Of Smooth Muscle Contraction Neural Nucleus Development
Tagcloud ?		a432t a452v ankk1 arrb2 cdh13 dbh dnm1 drd2 eas fagerstrom gabbr2 grin3a mstcc n549s nrxn1 nrxn2 nrxn3 ntrk2 r480h rs139982841 rs142807401 rs34755188 rs75981117 skat tas2r38 v132l v389l wss