U2AF2 and HNRNPA0

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		U2AF2	HNRNPA0
Gene Name		U2 small nuclear RNA auxiliary factor 2	heterogeneous nuclear ribonucleoprotein A0
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Prp19 Complex Nucleoplasm Spliceosomal Complex Nuclear Speck	Nucleus Nucleoplasm Ribonucleoprotein Complex
	Molecular Function	Nucleotide Binding Protein Binding Enzyme Binding Poly(A) RNA Binding C2H2 Zinc Finger Domain Binding	Nucleotide Binding RNA Binding AU-rich Element Binding Protein Kinase Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Positive Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome MRNA Processing Inflammatory Response RNA Splicing Gene Expression Response To Lipopolysaccharide 3'-UTR-mediated MRNA Stabilization
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		51 interactors: AES APBB1 ATXN1 BEND7 CCAR1 CHERP CHIC2 CPSF7 DACH1 DDX17 DDX6 DPPA2 DVL2 EPB41 GEMIN2 GLIS2 HLA-DMA HNRNPA0 HNRNPD HNRNPK IL7R KHDRBS1 KHDRBS3 KIAA0907 LURAP1 MAP1B PIN1 POLR2A PRPF3 PRPF40A PUF60 QKI RBFOX2 RBM39 RBM4 SAP30BP SCAF11 SF1 SMAD5 SNRPA SRPK1 SRPK2 SRSF1 SRSF11 SUGP1 TCERG1 THAP1 TOP1 U2AF1 WT1 ZRSR2	15 interactors: CCT3 CIRBP DDX5 HNRNPF HNRNPH2 HNRNPH3 HNRNPK IL7R MAPK6 MAPKAPK2 MTNR1A MTNR1B NKX3-1 SRSF1 U2AF2
Entrez ID		11338	10949
HPRD ID		01872	17112
Ensembl ID		ENSG00000063244	ENSG00000177733
Uniprot IDs		P26368	Q13151
PDB IDs		1JMT 1O0P 1OPI 1U2F 2G4B 2HZC 2M0G 2U2F 2YH0 2YH1 3VAF 3VAG 3VAH 3VAI 3VAJ 3VAK 3VAL 3VAM 4FXW
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing, Via Transesterification Reactions Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Ribonucleoprotein Complex Assembly Biosynthetic Process Spliceosomal Complex Assembly Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex Biogenesis Cellular Macromolecular Complex Assembly Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Metabolic Process Regulation Of MRNA Processing Termination Of RNA Polymerase II Transcription Regulation Of MRNA Stability Regulation Of RNA Stability Cellular Process DNA-templated Transcription, Termination Regulation Of Translation MRNA 3'-end Processing Positive Regulation Of Macromolecule Biosynthetic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Female Gonad Development Circadian Regulation Of Translation RNA 3'-end Processing	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Regulation Of RNA Splicing Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Gene Expression MRNA Stabilization Positive Regulation Of Gene Expression RNA Metabolic Process Termination Of RNA Polymerase II Transcription Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Response To DNA Damage Stimulus MRNA Export From Nucleus Regulation Of Gene Expression DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing Interleukin-7-mediated Signaling Pathway Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Androgen Secretion Regulation Of Lipid Transport Transcription From RNA Polymerase II Promoter Negative Regulation Of Estrogen Receptor Binding RNA 3'-end Processing Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Posttranscriptional Regulation Of Gene Expression Nuclear Export MRNA Transport Regulation Of Response To DNA Damage Stimulus MRNA 5'-splice Site Recognition Negative Regulation Of T Cell Mediated Cytotoxicity Nucleobase-containing Compound Metabolic Process RNA Transport Cell Growth G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger RNA Localization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Macropinocytosis Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Receptor Binding
Tagcloud ?		acceptor accessory advance alters codons corroborated cytidine doi junctions leu missense november novo online publication q157 q157p q157r s34 s34f s34y seq snrnp speckles splice splicing u2af1 uridine	atr cdc25b checkpoint chk1 contributions cytoplasm defective dissect entry feedback gadd45alpha genetics genotoxic initiate mitotic mk2 p38 parn phosphorylates posttranscriptional releases relocalizes rewire sequestration stabilization stabilize sustaining tiar unrepaired
Tagcloud (Difference) ?		acceptor accessory advance alters codons corroborated cytidine doi junctions leu missense november novo online publication q157 q157p q157r s34 s34f s34y seq snrnp speckles splice splicing u2af1 uridine	atr cdc25b checkpoint chk1 contributions cytoplasm defective dissect entry feedback gadd45alpha genetics genotoxic initiate mitotic mk2 p38 parn phosphorylates posttranscriptional releases relocalizes rewire sequestration stabilization stabilize sustaining tiar unrepaired
Tagcloud (Intersection) ?