LARP4 and LENG1

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		LARP4	LENG1
Description		La ribonucleoprotein 4	leukocyte receptor cluster member 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane Cytosolic Small Ribosomal Subunit	Nucleoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(A) Binding	Protein Binding
	Biological Process	Translation Cytoskeleton Organization Post-transcriptional Regulation Of Gene Expression Regulation Of Cell Morphogenesis Positive Regulation Of Translation
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic widespread musculoskeletal pain ( 33331911) Pulse pressure ( 30578418)	Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		25 interacting genes: APP BCAS2 BHLHE40 CRX EXOSC7 FNDC3B KAT5 LENG1 LRRK2 LSM5 PAX5 PAX6 PCM1 PFDN5 POU6F2 PRC1 PRPF39 PRPF6 TGM5 TXNL4A WBP4 YPEL3 YTHDF3 ZC3H7A ZNF830	90 interacting genes: ABI2 APP ASB12 BANP BEGAIN C14orf119 CALCOCO2 CARD10 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCHCR1 CDR2 CDR2L CEP55 CEP57L1 CEP70 CPSF7 DDIT4L DES DISC1 EVI5 EXOSC8 FSD2 GFAP GOLGA2 GOLGA6L9 HOMEZ HOOK1 HOOK2 IKZF3 ISY1-RAB43 KANK2 KASH5 KIFC3 KLF10 KRT19 KRT31 KRT35 KRT40 KRTAP10-8 LARP4 LDOC1 LRP2BP LZTS1 MAB21L3 MAD1L1 MEIS3 MID2 MIPOL1 MRPL28 MTUS2 NAB2 NAGK NECAB2 NTAQ1 NUTF2 OIP5 OSGEP PAK5 PDE4DIP PNMA1 PRKAR1B PRPH PSMB1 RABEP1 REL ROPN1 SCYL1 SPATA2 STX11 TCF4 TEPSIN TEX12 TFIP11 TMEM239 TRAF2 TRIB3 TRIM23 TRIM27 TRIM54 TSC1 UBL5 UBXN11 USHBP1 USO1 ZMYND12 ZRANB1
Entrez ID		113251	79165
HPRD ID		17289	13985
Ensembl ID		ENSG00000161813	ENSG00000105617
Uniprot IDs		Q6P4E2 Q71RC2 Q8TBL5 Q96J85	Q96BZ8
PDB IDs		2CQK 3PKN 6I9B
Enriched GO Terms of Interacting Partners?		Spliceosomal Complex RNA Splicing U2-type Precatalytic Spliceosome MRNA Processing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process U4/U6 X U5 Tri-snRNP Complex Cellular Response To Manganese Ion Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Manganese Ion Nucleus Retina Development In Camera-type Eye Golgi-associated Vesicle Regulation Of Amyloid Fibril Formation Cellular Response To Catecholamine Stimulus Cellular Component Assembly Response To Catecholamine U5 SnRNP Microtubule Cytoskeleton Organization Nucleoplasm Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Central Nervous System Development Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Microtubule-based Process Forebrain-midbrain Boundary Formation Pancreatic A Cell Development RNA Binding Establishment Of Mitotic Spindle Orientation RNA Polymerase III Assembly RNA Polymerase I Assembly Histone H2AK5 Acetyltransferase Activity Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly	Identical Protein Binding Cytoskeleton Protein Binding Intermediate Filament Organization Supramolecular Fiber Organization Cytoplasm Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytoskeleton Organization Intermediate Filament Centrosome Microtubule Binding Organelle Organization Microtubule Keratin Filament Regulation Of Autophagy Response To Muramyl Dipeptide Structural Constituent Of Cytoskeleton Microtubule-based Process Structural Constituent Of Skin Epidermis CBM Complex FHF Complex
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