LARP4 and TGM5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LARP4	TGM5
Description		La ribonucleoprotein 4	transglutaminase 5
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane Cytosolic Small Ribosomal Subunit	Cytoplasm Plasma Membrane
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(A) Binding	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Transferase Activity Acyltransferase Activity Metal Ion Binding
	Biological Process	Translation Cytoskeleton Organization Post-transcriptional Regulation Of Gene Expression Regulation Of Cell Morphogenesis Positive Regulation Of Translation	Epidermis Development Protein Modification Process
Pathways			Formation of the cornified envelope
Drugs
Diseases			Acral peeling skin syndrome
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic widespread musculoskeletal pain ( 33331911) Pulse pressure ( 30578418)	Household income (MTAG) ( 31844048) Lung cancer ( 19654303)
Interacting Genes		25 interacting genes: APP BCAS2 BHLHE40 CRX EXOSC7 FNDC3B KAT5 LENG1 LRRK2 LSM5 PAX5 PAX6 PCM1 PFDN5 POU6F2 PRC1 PRPF39 PRPF6 TGM5 TXNL4A WBP4 YPEL3 YTHDF3 ZC3H7A ZNF830	6 interacting genes: GRB7 KANK2 LARP4 LGALS7 LGALS7B RBM41
Entrez ID		113251	9333
HPRD ID		17289	11949
Ensembl ID		ENSG00000161813	ENSG00000104055
Uniprot IDs		Q6P4E2 Q71RC2 Q8TBL5 Q96J85	B4DPS8 O43548
PDB IDs		2CQK 3PKN 6I9B
Enriched GO Terms of Interacting Partners?		Spliceosomal Complex RNA Splicing U2-type Precatalytic Spliceosome MRNA Processing RNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process U4/U6 X U5 Tri-snRNP Complex Cellular Response To Manganese Ion Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Manganese Ion Nucleus Retina Development In Camera-type Eye Golgi-associated Vesicle Regulation Of Amyloid Fibril Formation Cellular Response To Catecholamine Stimulus Cellular Component Assembly Response To Catecholamine U5 SnRNP Microtubule Cytoskeleton Organization Nucleoplasm Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Central Nervous System Development Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Microtubule-based Process Forebrain-midbrain Boundary Formation Pancreatic A Cell Development RNA Binding Establishment Of Mitotic Spindle Orientation RNA Polymerase III Assembly RNA Polymerase I Assembly Histone H2AK5 Acetyltransferase Activity Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly	Cytoplasmic Stress Granule Negative Regulation Of Vitamin D Receptor Signaling Pathway U12 SnRNA Binding
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