CMTM7 and LDLRAD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CMTM7	LDLRAD1
Description		CKLF like MARVEL transmembrane domain containing 7	low density lipoprotein receptor class A domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Membrane	Membrane
	Molecular Function	Cytokine Activity Protein Binding	Protein Binding
	Biological Process	B-1a B Cell Differentiation Chemotaxis Signal Transduction	Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS		Copper levels ( 26025379) Hallux valgus ( 32131869) IgM levels ( 28628107) Metabolite levels ( 23823483) Mortality in heart failure ( 20400778) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Parkinson disease and lewy body pathology ( 25663231)
Interacting Genes		47 interacting genes: ADTRP AGER AQP6 ARL13B B3GAT1 BIK BSCL2 CD74 CD79A CLSTN3 CREB3L1 DAGLA DNAJC1 ELOVL4 FAM174A FAM209A FFAR2 FRMD3 GGT7 GORAB HAS3 HIBADH HSD17B13 LDLRAD1 LHFPL5 LMNA MS4A4A MUC1 PAGE1 PIANP PSMD6 RETREG3 SDC3 SHISA3 SLC14A2 SLC30A8 SSMEM1 STX1A TCTA TEX29 THAP4 TMEM106C TMEM174 TMEM31 TMPRSS2 TMX2 TNFRSF17	34 interacting genes: ADGRG7 ANKRD46 AQP1 BNIP2 BNIP3 BNIP3L CMTM7 CTXN3 CXCL9 EBP EMP3 GIMAP5 GPR25 IGFBP5 LAPTM5 MAL MALL MARCHF2 NINJ2 OLFM4 PLN PLPP6 PTTG1IP SEC22A SLC1A1 SLC41A2 TMEM147 TMEM190 TMEM218 TMEM79 UNC93B1 VAMP4 VTI1B ZFPL1
Entrez ID		112616	388633
HPRD ID		06988	17372
Ensembl ID		ENSG00000153551	ENSG00000203985
Uniprot IDs		F8WDZ3 Q96FZ5	Q5T700
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum	Membrane Presynaptic Endosome Membrane Cellular Response To Mercury Ion Positive Regulation Of Membrane Permeability Lysosome Nuclear Envelope Response To Mercury Ion Mitochondrial Protein Catabolic Process Endoplasmic Reticulum Membrane Mitochondrial Outer Membrane Permeabilization Structural Constituent Of Myelin Sheath Response To Oxygen-glucose Deprivation Neurotransmitter Receptor Transport To Plasma Membrane Defense Response To Virus Negative Regulation Of Mitochondrial Membrane Potential Protein Binding Negative Regulation Of Membrane Potential Response To Decreased Oxygen Levels Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Envelope Regulation Of Membrane Permeability Neurotransmitter Receptor Transport Response To Oxygen Levels Endoplasmic Reticulum Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Establishment Of Protein Localization Golgi To Vacuole Transport Establishment Of Protein Localization To Membrane Lysosomal Membrane Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Defense Response Nitric Oxide Transmembrane Transporter Activity Negative Regulation Of Programmed Cell Death Metanephric Proximal Convoluted Tubule Segment 2 Development Nuclear Membrane Membrane Organization Response To Virus Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Mitochondrial Membrane Permeability Mitochondrion Autophagosome Adaptor Activity Hair Follicle Morphogenesis Negative Regulation Of Skeletal Muscle Hypertrophy Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Circadian Sleep/wake Cycle, Sleep Phospholamban Complex Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Vesicle-mediated Transport D-aspartate Transmembrane Transporter Activity
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