CMTM7 and SDC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CMTM7	SDC3
Description		CKLF like MARVEL transmembrane domain containing 7	syndecan 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Membrane	Golgi Lumen Plasma Membrane Cell Surface Membrane Extracellular Matrix Lysosomal Lumen Microspike
	Molecular Function	Cytokine Activity Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	B-1a B Cell Differentiation Chemotaxis Signal Transduction	Cell Migration
Pathways			Glycosaminoglycan-protein linkage region biosynthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Cell surface interactions at the vascular wall Syndecan interactions Syndecan interactions Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Defective B3GALT6 causes EDSP2 and SEMDJL1 Attachment and Entry Attachment and Entry Retinoid metabolism and transport Respiratory syncytial virus (RSV) attachment and entry RSV-host interactions
Drugs
Diseases
GWAS		Copper levels ( 26025379) Hallux valgus ( 32131869) IgM levels ( 28628107) Metabolite levels ( 23823483) Mortality in heart failure ( 20400778) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Loneliness ( 27629369) Systolic blood pressure ( 34074324)
Interacting Genes		47 interacting genes: ADTRP AGER AQP6 ARL13B B3GAT1 BIK BSCL2 CD74 CD79A CLSTN3 CREB3L1 DAGLA DNAJC1 ELOVL4 FAM174A FAM209A FFAR2 FRMD3 GGT7 GORAB HAS3 HIBADH HSD17B13 LDLRAD1 LHFPL5 LMNA MS4A4A MUC1 PAGE1 PIANP PSMD6 RETREG3 SDC3 SHISA3 SLC14A2 SLC30A8 SSMEM1 STX1A TCTA TEX29 THAP4 TMEM106C TMEM174 TMEM31 TMPRSS2 TMX2 TNFRSF17	32 interacting genes: AGR2 CASK CMTM7 COL5A1 CSK CTTN CUX1 EPHB4 FGF2 FYN ITGB4 KCNJ2 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP2-3 KRTAP2-4 KRTAP4-2 KRTAP5-7 KRTAP5-9 KRTAP9-2 LCE3D MDK PLN PTN SLC35A1 SMIM1 TMEM14C TMEM218 TUBA1A TUBB TUBB2A
Entrez ID		112616	9672
HPRD ID		06988	01719
Ensembl ID		ENSG00000153551	ENSG00000162512
Uniprot IDs		F8WDZ3 Q96FZ5	O75056
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Endoplasmic Reticulum Membrane Endoplasmic Reticulum	Intermediate Filament Keratin Filament Response To Mechanical Stimulus Cell Motility Cell Migration Positive Regulation Of Blood Vessel Branching Regulation Of Blood Vessel Branching Regulation Of Calcium Ion Import Leukocyte Chemotaxis Involved In Inflammatory Response Integrin Binding Cell Projection Morphogenesis Positive Regulation Of Chemotaxis Learning Or Memory Chondroitin Sulfate Binding Positive Regulation Of Hepatocyte Proliferation Dendritic Spine Maintenance Estrous Cycle Heparin Binding Anatomical Structure Morphogenesis Learning Relaxation Of Cardiac Muscle Cognition Regulation Of Response To Wounding Regulation Of Hepatocyte Proliferation Basement Membrane Proline-rich Region Binding Regulation Of Chemotaxis Positive Regulation Of Cell Division Regulation Of Neural Precursor Cell Proliferation Positive Regulation Of Vascular Endothelial Cell Proliferation Response To L-glutamate Relaxation Of Muscle Positive Regulation Of Oligodendrocyte Differentiation Cerebral Cortex Development Response To Auditory Stimulus Ovulation Cycle Leukocyte Migration Involved In Inflammatory Response Neuron Projection Arborization Positive Regulation Of Neurogenesis Positive Regulation Of Stem Cell Differentiation Schaffer Collateral - CA1 Synapse Structural Constituent Of Cytoskeleton Identical Protein Binding Cell Migration Involved In Sprouting Angiogenesis Glial Cell Differentiation Calcium Ion Transport Dentate Gyrus Development Integrin Biosynthetic Process Developmental Process Protein Tyrosine Kinase Activity
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