GPR45 and REV1

		GPR45	REV1
Description		G protein-coupled receptor 45	REV1 DNA directed polymerase
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleus Nucleoplasm
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	DNA Binding Damaged DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Transferase Activity Nucleotidyltransferase Activity Deoxycytidyl Transferase Activity Metal Ion Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway	DNA Metabolic Process DNA Replication DNA Repair DNA Damage Response Response To UV Error-prone Translesion Synthesis Error-free Translesion Synthesis DNA Biosynthetic Process
Pathways		G alpha (s) signalling events	Translesion synthesis by REV1 Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis
Drugs
Diseases
GWAS		Body mass index ( 26426971) Menarche (age at onset) ( 25231870 27182965)	Bipolar disorder ( 21926972)
Interacting Genes		1 interacting genes: OTX2	13 interacting genes: CLK1 FAAP20 FHL2 MAD2L2 POLD3 POLDIP2 POLH POLI POLK POLL REV3L TSC22D2 UBC
Entrez ID		11250	51455
HPRD ID		05325	16202
Ensembl ID		ENSG00000135973	ENSG00000135945
Uniprot IDs		B5B0C1 Q9Y5Y3	Q49AI5 Q9UBZ9
PDB IDs			2EBW 2LSI 2LSK 2LSY 2N1G 3GQC 3VU7 4BA9 4EXT 4GK0 4GK5 5VZM 6ASR 6AXD 6WS0 6WS5
Enriched GO Terms of Interacting Partners?		Primitive Streak Formation Positive Regulation Of Embryonic Development Eukaryotic Initiation Factor 4E Binding Positive Regulation Of Gastrulation Regulation Of Gastrulation Doxorubicin Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Ethanol Metabolic Process Flavonoid Metabolic Process Sulfation Aryl Sulfotransferase Activity Ethanol Catabolic Process Error-free Translesion Synthesis Deoxycytidyl Transferase Activity Error-prone Translesion Synthesis DNA-directed DNA Polymerase Activity Translesion Synthesis Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Midbrain Development Dopaminergic Neuron Differentiation Alcohol Catabolic Process Postreplication Repair Sulfotransferase Activity Phosphatidylinositol-3,4,5-trisphosphate Binding DNA Synthesis Involved In DNA Repair Secondary Metabolic Process	Translesion Synthesis Postreplication Repair DNA Synthesis Involved In DNA Repair DNA Biosynthetic Process Error-prone Translesion Synthesis DNA-directed DNA Polymerase Activity DNA Polymerase Activity DNA Repair DNA Metabolic Process DNA Replication DNA Damage Response Zeta DNA Polymerase Complex Nucleobase-containing Compound Biosynthetic Process Nucleotidyltransferase Activity Macromolecule Biosynthetic Process Cellular Response To Stress Nucleic Acid Metabolic Process Error-free Translesion Synthesis Nucleotide-excision Repair, DNA Gap Filling Damaged DNA Binding Response To Stress Nucleobase-containing Compound Metabolic Process Site Of Double-strand Break Nucleoplasm Nucleus Somatic Diversification Of Immunoglobulins Double-strand Break Repair DNA-templated DNA Replication DNA Damage Response, Signal Transduction Resulting In Transcription Macromolecule Metabolic Process Transferase Activity Atrial Cardiac Muscle Cell Development Cellular Response To UV DNA Synthesis Involved In UV-damage Excision Repair Delta DNA Polymerase Complex Cellular Response To Light Stimulus Cellular Response To UV-C DNA Binding Vascular Associated Smooth Muscle Cell Proliferation
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