PKP3 and KRT18

Number of citations of the paper that reports this interaction (PMID 12707304)
37

Data Source:
BioGRID (two hybrid)

		PKP3	KRT18
Gene Name		plakophilin 3	keratin 18, type I
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Cell-cell Junction Desmosome	Nucleolus Cytoplasm Microtubule Organizing Center Intermediate Filament Centriolar Satellite Keratin Filament Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Cell Periphery
	Molecular Function	Cell Adhesion Molecule Binding	Structural Molecule Activity Protein Binding Poly(A) RNA Binding Scaffold Protein Binding
	Biological Process	Desmosome Assembly Single Organismal Cell-cell Adhesion Establishment Of Protein Localization To Plasma Membrane	Cell Cycle Anatomical Structure Morphogenesis Viral Process Tumor Necrosis Factor-mediated Signaling Pathway Golgi To Plasma Membrane CFTR Protein Transport Negative Regulation Of Apoptotic Process Intermediate Filament Cytoskeleton Organization Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSP JUP KRT18	73 interactors: BBS1 BBS2 BBS4 BBS7 CAMK2A CASP3 CASP6 CASP7 CASP8 CBL CCDC146 CCDC85B CCNI CDC5L CDK1 COL17A1 DEDD DNAJB6 EGFR EP300 EXOC8 FRAT1 GIT2 GOLGA2 GRN HAUS1 HGS HRAS HSPA1A HSPA4 HSPA5 IKBKG KPNA2 KRT15 KRT5 KRT72 KRT8 LDOC1 MAPK14 NME7 ORC5 PDE4DIP PIAS4 PKD1 PKP2 PKP3 PNN POT1 PRKCA PRKCE RAF1 RHPN2 RPS6KA3 SERPINE1 SHC1 SMARCD1 SUMO1 SVIL TCHP TNFRSF1B TRADD TUBG1 TUBGCP4 TXN2 TXNDC11 UPF2 USH2A YTHDC1 YWHAB YWHAE YWHAG YWHAH YWHAZ
Entrez ID		11187	3875
HPRD ID		05711	01020
Ensembl ID		ENSG00000184363	ENSG00000111057
Uniprot IDs		F8J390 Q9Y446	P05783
PDB IDs
Enriched GO Terms of Interacting Partners?		Bundle Of His Cell To Purkinje Myocyte Communication Ventricular Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Involved In Contraction Cardiac Muscle Cell Action Potential Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Regulation Of Striated Muscle Contraction Action Potential Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Cell Adhesion Regulation Of Muscle Contraction Regulation Of Heart Contraction Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Regulation Of Membrane Potential Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Regulation Of Actin Filament-based Process Single Organismal Cell-cell Adhesion Regulation Of Cellular Component Movement Desmosome Organization Apoptotic Process Programmed Cell Death Cell Death Death Cell-cell Junction Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Response To Progesterone Golgi To Plasma Membrane CFTR Protein Transport Establishment Of Protein Localization To Plasma Membrane Maternal Process Involved In Female Pregnancy Adherens Junction Organization Protein Stabilization Ventricular Compact Myocardium Morphogenesis Cell-cell Junction Assembly Signaling Cell Communication Endothelial Cell-cell Adhesion Regulation Of Protein Stability Cellular Response To Starvation Response To Stimulus Protein Localization To Plasma Membrane Desmosome Assembly Protein Localization To Adherens Junction Cellular Response To Indole-3-methanol	Apoptotic Process Programmed Cell Death Cell Death Death Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Regulation Of Apoptotic Process Neurotrophin Signaling Pathway Regulation Of Cellular Protein Metabolic Process Response To Organic Substance Cellular Response To Growth Factor Stimulus Response To Growth Factor Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway ERBB Signaling Pathway Cellular Component Assembly Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Communication Positive Regulation Of Cellular Protein Metabolic Process Membrane Organization Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Organelle Organization Innate Immune Response Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transport Anatomical Structure Development Mitotic Cell Cycle Regulation Of Cellular Component Organization Regulation Of Signaling Mitotic Cell Cycle Phase Transition Cellular Response To Fibroblast Growth Factor Stimulus Cell Cycle Phase Transition Enzyme Linked Receptor Protein Signaling Pathway Response To Fibroblast Growth Factor Developmental Process Defense Response Regulation Of Proteolysis Cellular Protein Localization Cellular Response To Stimulus
Tagcloud ?		ankrd33b asthma beadchip cntd2 concordant cpg detrimental dpp10 enrichment epigenome fetal goal gtf2h2c gtf2h2d humanmethylation450 illumina ius lung mapped methylation methylome nicotine origins placental smoke surrogate utero variation wheezing	actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf
Tagcloud (Difference) ?		ankrd33b asthma beadchip cntd2 concordant cpg detrimental dpp10 enrichment epigenome fetal goal gtf2h2c gtf2h2d humanmethylation450 illumina ius lung mapped methylation methylome nicotine origins placental smoke surrogate utero variation wheezing	actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf
Tagcloud (Intersection) ?