CCNI and IL1RAP

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CCNI	IL1RAP
Gene Name		cyclin I	interleukin 1 receptor accessory protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function		Signal Transducer Activity Interleukin-1 Receptor Activity
	Biological Process	Spermatogenesis Regulation Of Cell Cycle	Protein Complex Assembly Inflammatory Response Immune Response Cytokine-mediated Signaling Pathway Interleukin-2 Biosynthetic Process Innate Immune Response
Pathways
Drugs
Diseases
GWAS			Lung cancer ( 18385676) Waist circumference ( 20966902)
Protein-Protein Interactions		4 interactors: CDC25A CEP63 IL1RAP KRT18	19 interactors: CCNI IL18R1 IL1A IL1B IL1R1 IL1R2 IRAK1 KPNA1 MARCH8 MC4R MYD88 PIK3R1 PRKCI PRPF40A RAC1 SIRPA STAT3 TICAM2 TOLLIP
Entrez ID		10983	3556
HPRD ID		16690	04021
Ensembl ID		ENSG00000118816	ENSG00000196083
Uniprot IDs		B7Z6X4 Q14094	A8K6K4 Q9NPH3
PDB IDs			3O4O 4DEP
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Golgi To Plasma Membrane CFTR Protein Transport Interleukin-2 Biosynthetic Process Mitotic Cell Cycle Phase Transition Cell Cycle Cell Cycle Phase Transition Mitotic Nuclear Division Interleukin-2 Production Cell Division Centriole Replication Cytokine-mediated Signaling Pathway Hepatocyte Apoptotic Process Cellular Response To Cytokine Stimulus Centriole Assembly Cytokine Biosynthetic Process Golgi To Plasma Membrane Protein Transport Mitotic Cell Cycle Process Cytokine Metabolic Process Response To Cytokine Centrosome Duplication Mitotic Cell Cycle Golgi To Plasma Membrane Transport Tumor Necrosis Factor-mediated Signaling Pathway Cellular Response To Stimulus Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Organelle Organization Centrosome Cycle Cellular Response To UV Protein Complex Assembly Cell Cycle Process	Response To Cytokine Cytokine-mediated Signaling Pathway Cellular Response To Organic Substance Response To Organic Substance Cellular Response To Cytokine Stimulus Immune System Process Immune Response Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling Inflammatory Response Cell Surface Receptor Signaling Pathway Regulation Of Cytokine Production Positive Regulation Of Signal Transduction Signal Transduction Positive Regulation Of Cytokine Production Defense Response Response To Interleukin-1 Signaling Cell Communication Temperature Homeostasis Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Intracellular Signal Transduction Response To Organonitrogen Compound Positive Regulation Of NF-kappaB Transcription Factor Activity Fever Generation Acute-phase Response Cellular Response To Growth Factor Stimulus Positive Regulation Of Transcription Factor Import Into Nucleus Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Chemokine Production Intracellular Signal Transduction Cellular Response To Stimulus Response To Growth Factor Positive Regulation Of Protein Transport Negative Regulation Of Cell Death Cellular Response To Lipopolysaccharide Positive Regulation Of Immune Response Positive Regulation Of Intracellular Protein Transport Cellular Response To Molecule Of Bacterial Origin Regulation Of Protein Import Into Nucleus Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Interferon-gamma Production Regulation Of Establishment Of Protein Localization Regulation Of Chemokine Production Heat Generation Response To Stimulus
Tagcloud ?		analyze animal ccnd1 ccni2 cdk1 cdk16 cdk18 cdk3 cdk4 cdk8 cdk9 cdkis cdkn1a cdkn2a cdks comprehensive confirm cyclin database diabetic diagram islets microarray pancreatic pattern qrt reproduce snps t2d	36gamma 36r alarmin atopic augments camp cathelicidin ccl20 cxcl1 cxcl10 dermatitis dermatoses exacerbations il1rl2 il36g il36gamma il36r il8 ip10 keratinocytes lesional ll37 mip3a nonlesional occasional pertussis psoriasis rosacea wounding
Tagcloud (Difference) ?		analyze animal ccnd1 ccni2 cdk1 cdk16 cdk18 cdk3 cdk4 cdk8 cdk9 cdkis cdkn1a cdkn2a cdks comprehensive confirm cyclin database diabetic diagram islets microarray pancreatic pattern qrt reproduce snps t2d	36gamma 36r alarmin atopic augments camp cathelicidin ccl20 cxcl1 cxcl10 dermatitis dermatoses exacerbations il1rl2 il36g il36gamma il36r il8 ip10 keratinocytes lesional ll37 mip3a nonlesional occasional pertussis psoriasis rosacea wounding
Tagcloud (Intersection) ?