CCNI and CDK3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCNI	CDK3
Description		cyclin I	cyclin dependent kinase 3
Image		No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Cytoplasm Membrane Nuclear Membrane	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Cytoplasm
	Molecular Function	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Cyclin Binding Protein Serine Kinase Activity
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Spermatogenesis	G1/S Transition Of Mitotic Cell Cycle DNA Damage Response Signal Transduction Cell Population Proliferation Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Gene Expression G0 To G1 Transition Negative Regulation Of Notch Signaling Pathway Cell Division
Pathways
Drugs
Diseases
GWAS
Interacting Genes		10 interacting genes: AKT1 CDC25A CDK3 CDK6 CEP63 IL1RAP KRT18 MSRA RND1 ZMYND19	38 interacting genes: APP CABLES1 CABLES2 CCNA2 CCNC CCND3 CCNE1 CCNE2 CCNH CCNI CDC37 CDKN1A CDKN1B CDKN3 CKS2 E2F1 E2F2 E2F3 FOXP2 FRS2 KIR3DL1 LHX3 LHX4 MEOX2 NEDD4L NELFA OR2G6 OTX2 PAX5 PAX6 PAX8 PPARA RACGAP1 RB1 SPDYE4 STN1 TRIM55 TRIM63
Entrez ID		10983	1018
HPRD ID		16690	00446
Ensembl ID		ENSG00000118816	ENSG00000250506
Uniprot IDs		Q14094	Q00526
PDB IDs			7XQK 8H4R
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Cycle Phase Transition Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Process Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Mitotic Cell Cycle Phase Transition Cell Division Cell Cycle Phase Transition Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Mitotic Cell Cycle Cyclin Binding Regulation Of Cell Cycle Golgi To Plasma Membrane Protein Transport Negative Regulation Of Notch Signaling Pathway Cyclin-dependent Protein Kinase Holoenzyme Complex Establishment Of Protein Localization To Plasma Membrane Regulation Of TRNA Methylation Golgi To Plasma Membrane Transport Cyclin D2-CDK6 Complex L-methionine:thioredoxin-disulfide S-oxidoreductase Activity Peptide-methionine (S)-S-oxide Reductase Activity L-methionine-(S)-S-oxide Reductase Activity Negative Regulation Of Protein Ubiquitination Cellular Response To Stress Protein Serine Kinase Activity Negative Regulation Of Protein Localization To Lysosome Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex FBXO Family Protein Binding Interleukin-33 Receptor Activity Negative Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Localization To Endoplasmic Reticulum Cytokine-mediated Signaling Pathway Regulation Of Notch Signaling Pathway Post-Golgi Vesicle-mediated Transport Response To Insulin-like Growth Factor Stimulus Positive Regulation Of Mitotic Cell Cycle Phase Transition Mammalian Oogenesis Stage TRNA (guanine-N7)-methylation Cellular Response To Rapamycin Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway Protein Serine/threonine Kinase Activity Positive Regulation Of Endodeoxyribonuclease Activity Positive Regulation Of G2/MI Transition Of Meiotic Cell Cycle Positive Regulation Of Cell Cycle Phase Transition Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Protein Kinase Binding TORC2 Complex Binding	Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cyclin-dependent Protein Kinase Holoenzyme Complex Protein Kinase Binding Regulation Of Primary Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Chromatin Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Sequence-specific DNA Binding Rb-E2F Complex Regulation Of Macromolecule Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Metabolic Process DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cell Division Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Cell Population Proliferation Regulation Of Gene Expression Epithelial Cell Apoptotic Process Negative Regulation Of Cardiac Muscle Tissue Regeneration Medial Motor Column Neuron Differentiation Regulation Of Phosphorus Metabolic Process Regulation Of Cell Cycle Phase Transition DNA Binding Positive Regulation Of Mitotic Cell Cycle Cyclin E1-CDK2 Complex Regulation Of Protein Kinase Activity
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