PLA2G3

Gene Name		phospholipase A2, group III
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Centriole Plasma Membrane Mast Cell Granule
	Molecular Function	Calcium Ion Binding Calcium-dependent Phospholipase A2 Activity
	Biological Process	Acrosome Assembly Phospholipid Metabolic Process Sperm Axoneme Assembly Lipid Catabolic Process Lipoxygenase Pathway Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Mast Cell Degranulation Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process Cilium Morphogenesis
Pathways		Acyl chain remodelling of PG Acyl chain remodelling of PE Metabolism of lipids and lipoproteins Phospholipid metabolism Glycerophospholipid biosynthesis Acyl chain remodelling of PC
Drugs
Diseases
GWAS		Paclitaxel-induced neuropathy ( 23776197)
Protein-protein Interactions		2 interactors: PVR TGFB1I1
Entrez ID		50487
HPRD ID		07144
Ensembl ID		ENSG00000100078
Uniprot IDs		Q9NZ20
PDB IDs
Enriched GO Terms of Interacting Partners?		Susceptibility To T Cell Mediated Cytotoxicity Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Ubiquitin-dependent SMAD Protein Catabolic Process Positive Regulation Of Immune Response To Tumor Cell Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell Adhesion Positive Regulation Of Epithelial To Mesenchymal Transition Androgen Receptor Signaling Pathway Viral Entry Into Host Cell Entry Into Host Cell Positive Regulation Of Stem Cell Differentiation Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of T Cell Mediated Cytotoxicity Adherens Junction Organization Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Leukocyte Mediated Cytotoxicity Interaction With Host Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of T Cell Mediated Immunity Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Cell Killing Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Leukocyte Mediated Cytotoxicity Response To Heat Regulation Of Fat Cell Differentiation Positive Regulation Of Adaptive Immune Response Positive Regulation Of Cell Morphogenesis Involved In Differentiation Morphogenesis Of Embryonic Epithelium Positive Regulation Of Innate Immune Response Regulation Of Cellular Response To Growth Factor Stimulus Response To Temperature Stimulus Viral Life Cycle Regulation Of Adaptive Immune Response Intracellular Receptor Signaling Pathway Cell Junction Assembly Cell-cell Junction Organization
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