KDELR1 and SEC23B

Number of citations of the paper that reports this interaction (PubMedID 9472029)
69

Data Source:
BioGRID (unspecified method)

		KDELR1	SEC23B
Description		KDEL endoplasmic reticulum protein retention receptor 1	SEC23 homolog B, COPII component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Membrane Transport Vesicle COPI-coated Vesicle Membrane Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Membrane COPII Vesicle Coat Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	KDEL Sequence Binding Protein Binding ER Retention Sequence Binding	GTPase Activator Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Protein Retention In ER Lumen Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Vesicle-mediated Transport T Cell Differentiation T Cell Apoptotic Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport COPII-coated Vesicle Cargo Loading COPII-coated Vesicle Budding
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases			Congenital dyserythropoietic anemias (CDAs)
GWAS			Refractive error ( 32231278)
Interacting Genes		12 interacting genes: ARF1 ARFGAP1 CCR9 COPB1 DLG2 DLG3 F2RL1 GPR35 KRT34 LIG4 PRKACA SEC23B	26 interacting genes: CPSF7 DTX2 FATE1 FBXW5 GALNT1 HOXA3 KDELR1 MAN2A1 PRRC1 RIN1 SEC24C SEC24D SKP1 SNRPC SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 TRIM55 TRIM63 UBA52 UBC UGT1A1
Entrez ID		10945	10483
HPRD ID		00569	11543
Ensembl ID		ENSG00000105438	ENSG00000101310
Uniprot IDs		P24390	A0A2R8YFH5 Q15437
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Protein Transport Neuromuscular Junction Protein Transport Regulation Of Endocytosis Intracellular Protein Localization Establishment Of Protein Localization Chemokine Receptor Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Ionotropic Glutamate Receptor Binding Cellular Localization Magnesium Ion Binding Regulation Of Biological Quality Mitotic Cleavage Furrow Ingression Regulation Of Vesicle-mediated Transport Receptor Clustering Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Receptor Localization To Synapse Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream Establishment Of Integrated Proviral Latency Protein Localization To Synapse Intracellular Transport Cleavage Furrow Ingression Retrograde Axonal Protein Transport Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Proteinase-activated Receptor Activity Mononuclear Cell Differentiation Positive Regulation Of Phagocytosis T Cell Activation Positive Regulation Of Eosinophil Degranulation Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Chemokine-mediated Signaling Pathway Establishment Of Viral Latency Neuron Projection Protein Localization To Cell Junction Positive Regulation Of Glomerular Filtration G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Activity Regulation Of Renin Secretion Into Blood Stream Leukocyte Differentiation Negative Regulation Of Toll-like Receptor 3 Signaling Pathway DNA Ligase (ATP) Activity DNA Ligase IV Complex DNA Ligase Activity CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Kinase Binding Regulation Of Phagocytosis Establishment Of Localization In Cell Postsynaptic Density Membrane	Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPI Coating Of Golgi Vesicle Vesicle Cargo Loading Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Vesicle Transport COPII-coated ER To Golgi Transport Vesicle ER To Golgi Transport Vesicle Membrane Protein Modification Process Transport Vesicle Vesicle Coating Protein Ubiquitination Golgi Organization Maintenance Of Protein Localization In Organelle Cis-Golgi Network Endoplasmic Reticulum Protein Modification By Small Protein Conjugation Maintenance Of Protein Location In Cell Maintenance Of Protein Location Intracellular Protein Transport Maintenance Of Location In Cell COPI-coated Vesicle Post-translational Protein Modification Protein Tag Activity Maintenance Of Location COPII Vesicle Coat COPI-coated Vesicle Membrane Vesicle-mediated Transport Zymogen Granule Membrane Trans-Golgi Network Transport Vesicle COPII-coated Vesicle Cargo Loading Golgi Membrane In Utero Embryonic Development Chordate Embryonic Development COPII Vesicle Coating Golgi Apparatus Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Viral Protein Processing Endoplasmic Reticulum Exit Site Positive Regulation Of Viral Genome Replication Protein Transport Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Metabolic Process
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