YIF1A and SLCO2B1

		YIF1A	SLCO2B1
Description		Yip1 interacting factor homolog A, membrane trafficking protein	solute carrier organic anion transporter family member 2B1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Membrane COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Plasma Membrane Basal Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding	Organic Anion Transmembrane Transporter Activity Bile Acid Transmembrane Transporter Activity Prostaglandin Transmembrane Transporter Activity Sodium-independent Organic Anion Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Vesicle-mediated Transport	Xenobiotic Metabolic Process Monoatomic Ion Transport Organic Anion Transport Bile Acid And Bile Salt Transport Prostaglandin Transport Heme Catabolic Process Sodium-independent Organic Anion Transport Transmembrane Transport Transport Across Blood-brain Barrier
Pathways		XBP1(S) activates chaperone genes	Organic anion transport by SLCO transporters
Drugs			Gemfibrozil Telaprevir
Diseases
GWAS		Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)
Interacting Genes		71 interacting genes: APOA5 AQP6 ARLN BNIP2 CD79A CDK2AP2 CERS2 CNRIP1 CST6 EBP ELOVL4 ERGIC3 FAM210B FARS2 FCER1G FFAR2 GAS7 GJA8 GPR37 GPR42 GPX8 JOSD2 LNPK LSS MARCHF5 MGST3 MIEF2 MLLT1 MMGT1 MSMO1 MTERF3 MYG1 NDRG4 PLEKHF2 PPIF PTGES PTPN9 RBFA REEP2 REEP4 RIC3 RNF144A SCN3B SCN4B SDCBP SEC23IP SLC10A1 SLC34A1 SLC35H1 SNX10 SNX11 SNX2 SYTL2 SYTL5 TIMMDC1 TMEM139 TMEM14B TMEM17 TMEM225B TMEM248 TMEM31 TMX2 VKORC1 VMA21 WDFY2 YIPF4 YIPF5 ZDHHC16 ZDHHC17 ZFYVE21 ZFYVE27	1 interacting genes: APP
Entrez ID		10897	11309
HPRD ID		06755	07061
Ensembl ID		ENSG00000174851	ENSG00000137491
Uniprot IDs		A6NGW1 A8K509 O95070	A0A0A0MTF1 O94956
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Protein Binding Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Glutathione Peroxidase Activity Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential Regulation Of Mast Cell Apoptotic Process Endoplasmic Reticulum Organization	Acetylcholine Receptor Activator Activity Membrane Raft Amyloid-beta Complex PTB Domain Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Integrin Binding Regulation Of Leukocyte Migration Regulation Of Response To Calcium Ion Cell Activation Involved In Immune Response Amylin Binding Response To Amyloid-beta Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Amyloid-beta Lipoprotein Particle Positive Regulation Of Leukocyte Migration Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of ERK1 And ERK2 Cascade Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of ERK1 And ERK2 Cascade Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Membrane To Membrane Docking T Cell Antigen Processing And Presentation T Cell Extravasation Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition External Side Of Plasma Membrane Receptor-mediated Virion Attachment To Host Cell Heparan Sulfate Binding Signaling Receptor Activator Activity T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
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