SLCO2B1

Description		solute carrier organic anion transporter family member 2B1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Basal Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	Organic Anion Transmembrane Transporter Activity Bile Acid Transmembrane Transporter Activity Prostaglandin Transmembrane Transporter Activity Sodium-independent Organic Anion Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Xenobiotic Metabolic Process Monoatomic Ion Transport Organic Anion Transport Bile Acid And Bile Salt Transport Prostaglandin Transport Heme Catabolic Process Sodium-independent Organic Anion Transport Transmembrane Transport Transport Across Blood-brain Barrier
Pathways		Organic anion transport by SLCO transporters
Drugs		Gemfibrozil Telaprevir
Diseases
GWAS
Novel Interacting Genes		2 novel interacting genes: ICAM1 YIF1A
Interacting Genes		1 interacting genes: APP
Entrez ID		11309
HPRD ID		07061
Ensembl ID		ENSG00000137491
Uniprot IDs		A0A0A0MTF1 O94956
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Membrane Raft Amyloid-beta Complex PTB Domain Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Integrin Binding Regulation Of Leukocyte Migration Regulation Of Response To Calcium Ion Cell Activation Involved In Immune Response Amylin Binding Response To Amyloid-beta Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Amyloid-beta Lipoprotein Particle Positive Regulation Of Leukocyte Migration Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of ERK1 And ERK2 Cascade Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of ERK1 And ERK2 Cascade Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Membrane To Membrane Docking T Cell Antigen Processing And Presentation T Cell Extravasation Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition External Side Of Plasma Membrane Receptor-mediated Virion Attachment To Host Cell Heparan Sulfate Binding Signaling Receptor Activator Activity T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
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