USP20 and TRIM23

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		USP20	TRIM23
Gene Name		ubiquitin specific peptidase 20	tripartite motif containing 23
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Perinuclear Region Of Cytoplasm	Golgi Membrane Nucleus Lysosomal Membrane Extracellular Vesicular Exosome
	Molecular Function	G-protein Coupled Receptor Binding Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding	GTPase Activity Ubiquitin-protein Transferase Activity Protein Binding GTP Binding Enzyme Activator Activity Zinc Ion Binding Ligase Activity GDP Binding Identical Protein Binding
	Biological Process	Endocytosis Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Protein Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination	Small GTPase Mediated Signal Transduction Viral Process Protein Ubiquitination Positive Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: ALAS1 BEND5 BEND7 CCDC36 DIO2 FATE1 HIF1A MAGEA11 MDFI PJA1 PLA2G2A PRKCI RAD17 SPRY2 TRIM23 USP15 USP21 USP28 VAPB VHL	137 interactors: AKTIP ANKRD36BP1 AQP1 ARFGAP1 ARHGEF3 ARNT2 ATPAF2 ATXN7 BAG1 C10orf10 C19orf57 C8orf33 CARD9 CCDC146 CCDC25 CDC20B CDR2 CFAP53 COX5B CREB5 CXCL14 CYTH1 CYTH2 DCX DMC1 DMRT3 DOCK2 EAF2 EXOC3-AS1 FAM103A1 FAM110A FAM133A FAM193B FAM208B FAM83A FAM90A1 FBF1 FHIT FLAD1 FLJ38668 FXR2 GATA2 GEM GGA2 GMCL1P1 GPANK1 GPKOW HAUS1 HOXB5 HSPB7 IQCE IQUB JOSD1 KAT5 KIFC3 KLHL42 KRT6A LGALS8 LINC00526 LINC01018 LMO2 LNX1 LOC729603 MDM2 MKRN3 MLH1 MORN4 MRPL4 MRPL45 MTFR2 NEK6 NFU1 NXT2 PHF1 PIAS2 PIK3R2 PITX1 PKP4 POLI POLL POM121 PPIL2 PPP1R18 PSMA1 RAD18 RIBC2 RNF126 RNF213 RNF32 RNF34 RSRC2 RTP5 SF1 SH2D4A SIAH1 SLC25A6 SMG9 SNAI1 SNAI2 SNRPB SORBS3 SPG21 STK19 SUMO1P1 TBC1D22B TMSB4X TNFAIP3 TRAF1 TRAIP TRIM27 TRIM29 TRIM31 TRIM32 TRIM42 TROAP TSG101 TSHZ3 TXNDC5 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2H UBE2I UBE2U UBOX5 USP2 USP20 USP21 UTP23 WDR25 ZC2HC1C ZNF250 ZNF564 ZNF581
Entrez ID		10868	373
HPRD ID		07505	03449
Ensembl ID		ENSG00000136878	ENSG00000113595
Uniprot IDs		Q9Y2K6	P36406
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Deubiquitination Protein Modification By Small Protein Removal Cellular Metabolic Process Histone Deubiquitination Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Stress Regulation Of Proteasomal Protein Catabolic Process Localization Within Membrane Protein Catabolic Process Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Proteasomal Protein Catabolic Process Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation By Host Of Viral Release From Host Cell Neural Fold Elevation Formation Embryonic Organ Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Membrane Budding Histone H2B Conserved C-terminal Lysine Deubiquitination Elastin Metabolic Process Negative Regulation By Virus Of Viral Protein Levels In Host Cell Negative Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Release From Host Cell Thyroid Hormone Catabolic Process Response To Interleukin-1 Regulation Of Cell Proliferation Positive Regulation Of Cell Differentiation Regulation Of Protein Catabolic Process Cellular Response To Hypoxia Cellular Response To Stimulus Cellular Response To Decreased Oxygen Levels Positive Regulation Of Catalytic Activity Cellular Protein Modification Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Chemokine-mediated Signaling Pathway Vascular Endothelial Growth Factor Production Negative Regulation Of Apoptotic Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Programmed Cell Death Cellular Protein Metabolic Process Establishment Of Cell Polarity Cellular Response To Oxygen Levels Response To Stimulus Protein Metabolic Process Embryonic Placenta Development	Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Regulation Of Protein Catabolic Process Proteolysis Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Programmed Cell Death Regulation Of Metabolic Process Cellular Response To Stress Positive Regulation Of Metabolic Process Cell Death Death Gene Expression RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Biosynthetic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia Protein Metabolic Process Cellular Response To Decreased Oxygen Levels Regulation Of Transcription, DNA-templated Regulation Of Proteolysis Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Oxygen Levels Regulation Of Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process
Tagcloud ?		ablated adrenergic arrestin ars betaar blocker carvedilol desensitization deubiquitinases e3 endogenously flag hek interacted internalized itinerary ligase lysosomal machineries march2 proteomics recruit recycling serves stabilized ubiquitinated ubiquitination usp33 vsmcs	344r abrogated adaptor antiviral conjugation defense e3 ectopic embryo helicase ikkgamma innate irf3 k165 k27 lys mda5 modulator multipoints nemo polyubiquitination rig substantially tightly tlr3 tlrs toll triparite ubiquitin
Tagcloud (Difference) ?		ablated adrenergic arrestin ars betaar blocker carvedilol desensitization deubiquitinases endogenously flag hek interacted internalized itinerary ligase lysosomal machineries march2 proteomics recruit recycling serves stabilized ubiquitinated ubiquitination usp33 vsmcs	344r abrogated adaptor antiviral conjugation defense ectopic embryo helicase ikkgamma innate irf3 k165 k27 lys mda5 modulator multipoints nemo polyubiquitination rig substantially tightly tlr3 tlrs toll triparite ubiquitin
Tagcloud (Intersection) ?		e3