NOXA1 and KRTAP19-7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NOXA1	KRTAP19-7
Description		NADPH oxidase activator 1	keratin associated protein 19-7
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane NADPH Oxidase Complex	Cytosol Intermediate Filament
	Molecular Function	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Small GTPase Binding Identical Protein Binding	Protein Binding
	Biological Process	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Superoxide Anion Generation Regulation Of Respiratory Burst
Pathways		RHO GTPases Activate NADPH Oxidases RAC1 GTPase cycle RAC3 GTPase cycle WNT5:FZD7-mediated leishmania damping	Keratinization
Drugs
Diseases
GWAS		Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		57 interacting genes: ACTMAP ANKRD55 CACNA1A CEP70 CFP CRYBA1 CTDSP1 CYSRT1 DCLRE1B DDAH2 DUSP4 EP300 FAT1 GATAD2B IL16 KCTD15 KRTAP13-1 KRTAP15-1 KRTAP19-4 KRTAP19-7 KRTAP8-1 LASP1 LMO2 MAPK1 MAPK11 METTL27 MORN3 MYLIP NAA10 NADSYN1 NCF1 NDUFAB1 NOX1 NOXO1 PFDN5 PLA2G10 PRKACA PRKCA PRKCG QARS1 RAC1 RAC2 REL RIMBP3 RIMBP3C SMUG1 SPMIP6 TCF19 TCF4 TGS1 TRAF2 TRIM23 UBAP2 WDR83 ZC2HC1C ZNF474 ZNF620	83 interacting genes: ANKS1A ARID5A ARMC7 ATPAF2 ATXN1L BAHD1 BHLHE40 C11orf16 CAMK2A CAMK2B CATSPER1 CCDC24 CCNK COL8A1 CYSRT1 DAB1 DAZAP2 DTX2 EVX2 FAM168A FOXD2 FOXH1 FOXI1 GLIS2 GNE GSX1 HOMER3 HOXA1 HSF4 IRX6 KPRP KRT34 KRTAP10-8 KRTAP12-3 KRTAP12-4 KRTAP26-1 KRTAP3-3 KRTAP6-3 KRTAP9-2 LONRF1 MAPK1IP1L MGAT5B MKRN3 NAF1 NEU4 NOTO NOXA1 OTX1 PATZ1 PAX7 PITX1 PITX2 PLSCR3 PLSCR4 POU2AF1 POU4F2 PROP1 PRR13 PSMB1 PSMB2 RBPMS RBPMS2 RHOXF2 RNF44 ROR2 SMN1 SMN2 SPAG8 SPMIP9 TCAP TCF7L2 TEKT5 TFAP2D TLE5 TLX3 TNIP1 TOLLIP TPRX1 VAC14 VENTX VGLL3 VPS37C ZIC1
Entrez ID		10811	337974
HPRD ID		17644	11211
Ensembl ID		ENSG00000188747	ENSG00000244362
Uniprot IDs		Q86UR1	Q3SYF9
PDB IDs		7CFZ
Enriched GO Terms of Interacting Partners?		NADPH Oxidase Complex Superoxide Anion Generation Superoxide Metabolic Process Regulation Of Respiratory Burst Respiratory Burst Regulation Of Hydrogen Peroxide Metabolic Process Reactive Oxygen Species Metabolic Process Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Manchette Benzodiazepine Receptor Binding Erythrocyte Enucleation Protein Binding Intermediate Filament Signal Transduction Involved In Regulation Of Gene Expression Regulation Of Cytokine Production Superoxide-generating NADPH Oxidase Activator Activity Intracellular Signaling Cassette Internal Protein Amino Acid Acetylation Negative Regulation Of Glial Cell Apoptotic Process Thioesterase Binding	Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Intermediate Filament Sequence-specific DNA Binding Keratin Filament Identical Protein Binding Nucleus Cellular Developmental Process Cell Differentiation Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Developmental Process Regionalization Myoblast Fate Commitment Regulation Of Macromolecule Biosynthetic Process Central Nervous System Development Positive Regulation Of Biosynthetic Process Pattern Specification Process Somatotropin Secreting Cell Differentiation Anatomical Structure Morphogenesis Transcription Regulator Complex Axonemal A Tubule Inner Sheath Embryonic Morphogenesis Calcium- And Calmodulin-dependent Protein Kinase Complex Positive Regulation Of Macromolecule Metabolic Process Transcription Cis-regulatory Region Binding Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Neuron Differentiation System Development Pituitary Gland Development Muscle Tissue Morphogenesis Adenohypophysis Development
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