NOXA1 and NOXO1

Number of citations of the paper that reports this interaction (PMID 12716910)
66

Data Source:
HPRD (in vivo, two hybrid)

		NOXA1	NOXO1
Gene Name		NADPH oxidase activator 1	NADPH oxidase organizer 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm NADPH Oxidase Complex	NADPH Oxidase Complex
	Molecular Function	Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Rac GTPase Binding	Protein Binding Phospholipid Binding Superoxide-generating NADPH Oxidase Activator Activity Enzyme Binding Phosphatidylinositol Binding Identical Protein Binding
	Biological Process	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Positive Regulation Of Catalytic Activity Regulation Of Respiratory Burst	Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Extracellular Matrix Disassembly Positive Regulation Of Catalytic Activity Regulation Of Respiratory Burst
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CACNA1A DYT10 EP300 MAPK1 MAPK11 NCF1 NOXO1 PRKACA PRKCG RAC1 RAC2 RIMBP3	1 interactors: NOXA1
Entrez ID		10811	124056
HPRD ID		17644	14834
Ensembl ID		ENSG00000188747	ENSG00000196408
Uniprot IDs		Q86UR1	A8K832 Q8NFA2
PDB IDs			2L73
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Signaling Pathway Innate Immune Response Regulation Of Hydrogen Peroxide Metabolic Process Platelet Activation Regulation Of Respiratory Burst Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Immune Response Defense Response Response To Stress Blood Coagulation Hemostasis Enzyme Linked Receptor Protein Signaling Pathway Cell Death Death Intracellular Signal Transduction Regulation Of Body Fluid Levels Cellular Response To Growth Factor Stimulus Wound Healing Response To Growth Factor Cell Activation Response To Wounding Immune System Process Positive Regulation Of Cell Migration Nervous System Development Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Signal Transduction Positive Regulation Of Chemotaxis Positive Regulation Of Catalytic Activity Positive Regulation Of Lamellipodium Assembly Positive Regulation Of Immune System Process Positive Regulation Of Behavior Signaling Positive Regulation Of Lamellipodium Organization Regulation Of Chemotaxis Cell Communication Apoptotic Process Programmed Cell Death Regulation Of Reactive Oxygen Species Metabolic Process Response To External Stimulus Positive Regulation Of Kinase Activity Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Organic Substance Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Neutrophil Chemotaxis	Regulation Of Hydrogen Peroxide Metabolic Process Regulation Of Respiratory Burst Superoxide Metabolic Process Reactive Oxygen Species Metabolic Process Regulation Of Reactive Oxygen Species Metabolic Process
Tagcloud ?		accumulates agonistic anion capability conventionally dr4 dr5 eventual fc fused jurkat kd548 kringle nadph negligible nox1 noxo1 proapoptotic rac1 recombinantly recruit recruiting rfk riboflavin ros stabilizes tradd traf2 trail	17c 6j alcoholic b6 card ccl4 chronically conferred congenic congenics css csss decarli etoh fibrosis inbred lieber nash nlr nlrc4 nonalcoholic obrq13 obrq15 organizer qtl qtls steatohepatitis steatosis tetrachloride
Tagcloud (Difference) ?		accumulates agonistic anion capability conventionally dr4 dr5 eventual fc fused jurkat kd548 kringle nadph negligible nox1 proapoptotic rac1 recombinantly recruit recruiting rfk riboflavin ros stabilizes tradd traf2 trail	17c 6j alcoholic b6 card ccl4 chronically conferred congenic congenics css csss decarli etoh fibrosis inbred lieber nash nlr nlrc4 nonalcoholic obrq13 obrq15 organizer qtl qtls steatohepatitis steatosis tetrachloride
Tagcloud (Intersection) ?		noxo1