LAMC3 and KIF1C

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		LAMC3	KIF1C
Description		laminin subunit gamma 3	kinesin family member 1C
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Membrane Extracellular Matrix	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytoskeleton Kinesin Complex Microtubule Axon Dendrite Axon Cytoplasm
	Molecular Function	Structural Molecule Activity	Nucleotide Binding RNA Binding Cytoskeletal Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity ATP Hydrolysis Activity
	Biological Process	Cell Morphogenesis Cell Adhesion Visual Perception Astrocyte Development Retina Development In Camera-type Eye	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Vesicle-mediated Transport Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport
Pathways		Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions MET activates PTK2 signaling Attachment of bacteria to epithelial cells Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC) Developmental Lineage of Pancreatic Ductal Cells	COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Alcohol consumption (max-drinks) ( 29460428) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Degraded stimulus continuous performance test score ( 31596458) Endometriosis ( 28333195) Oral cavity and pharyngeal cancer ( 27749845) Oral cavity cancer ( 27749845) Smoking status (heavy vs never) ( 26423011)	Mean spheric corpuscular volume ( 32888494) Reticulocyte count ( 32888494) Spleen volume ( 34128465)
Interacting Genes		20 interacting genes: ANXA5 CFB CRP CSNK2A2 CWC25 CYP2E1 EPB41L4B FRAT1 HP KIF1C LGMN NR1H2 PELI2 POT1 RPL35 SERPINA3 SLC43A3 TF YTHDC1 ZNF160	10 interacting genes: CSNK2A1 CSNK2A2 LAMC3 PTPN21 RNF10 TSC1 YWHAB YWHAE YWHAG YWHAZ
Entrez ID		10319	10749
HPRD ID		05069	04342
Ensembl ID		ENSG00000050555	ENSG00000129250
Uniprot IDs		Q8N2D6 Q9Y6N6	O43896
PDB IDs			2G1L 9KO8
Enriched GO Terms of Interacting Partners?		Acute-phase Response Blood Microparticle Acute Inflammatory Response Response To Bacterium Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Lipid Storage	Phosphoserine Residue Binding Protein Sequestering Activity Protein Targeting Protein Kinase CK2 Complex Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of TORC1 Signaling TORC1 Signaling Protein Domain Specific Binding Cerebral Cortex Development TOR Signaling Negative Regulation Of TOR Signaling Regulation Of TORC1 Signaling Melanosome Regulation Of Protein Stability Focal Adhesion Regulation Of Protein Localization Regulation Of TOR Signaling Cellular Response To Stress PcG Protein Complex Cellular Response To Starvation Regulation Of Macroautophagy Phosphoprotein Binding Hsp90 Protein Binding Response To Starvation Protein Catabolic Process Protein Stabilization Protein Phosphatase Inhibitor Activity Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Translational Initiation Negative Regulation Of Protein Localization To Nucleus Cellular Response To Glucose Starvation Cellular Response To Nutrient Levels Regulation Of Signal Transduction Signal Transduction Establishment Of Protein Localization Negative Regulation Of Proteasomal Protein Catabolic Process Memory T Cell Differentiation Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of TORC1 Signaling Negative Regulation Of Intracellular Signal Transduction Cadherin Binding Hippocampus Development Regulation Of Cell Communication Regulation Of Signaling Regulation Of Chromosome Separation Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Catabolic Process Regulation Of Autophagy
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