LAMC3 and EPB41L4B

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		LAMC3	EPB41L4B
Description		laminin subunit gamma 3	erythrocyte membrane protein band 4.1 like 4B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Membrane Extracellular Matrix	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Bicellular Tight Junction Apical Part Of Cell Anchoring Junction
	Molecular Function	Structural Molecule Activity	Structural Constituent Of Cytoskeleton Cytoskeletal Protein Binding
	Biological Process	Cell Morphogenesis Cell Adhesion Visual Perception Astrocyte Development Retina Development In Camera-type Eye	Positive Regulation Of Gene Expression Regulation Of Keratinocyte Proliferation Actomyosin Structure Organization Wound Healing Positive Regulation Of Cell Adhesion Positive Regulation Of Keratinocyte Migration
Pathways		Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions MET activates PTK2 signaling Attachment of bacteria to epithelial cells Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC) Developmental Lineage of Pancreatic Ductal Cells
Drugs
Diseases
GWAS		Alcohol consumption (max-drinks) ( 29460428) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Degraded stimulus continuous performance test score ( 31596458) Endometriosis ( 28333195) Oral cavity and pharyngeal cancer ( 27749845) Oral cavity cancer ( 27749845) Smoking status (heavy vs never) ( 26423011)	Adult body size ( 32376654) Alanine aminotransferase levels ( 33547301) Body mass index ( 25673413 28892062) Degraded stimulus continuous performance test score ( 31596458) High density lipoprotein cholesterol levels ( 33339817) Liver enzyme levels (alanine transaminase) ( 33972514) Low vWF levels ( 26486471) Staphylococcus aureus nasal carriage (persistent) ( 26569114) Umami taste perception in obesity with metabolic syndrome ( 31005965)
Interacting Genes		20 interacting genes: ANXA5 CFB CRP CSNK2A2 CWC25 CYP2E1 EPB41L4B FRAT1 HP KIF1C LGMN NR1H2 PELI2 POT1 RPL35 SERPINA3 SLC43A3 TF YTHDC1 ZNF160	2 interacting genes: LAMC3 SRPK2
Entrez ID		10319	54566
HPRD ID		05069	09940
Ensembl ID		ENSG00000050555	ENSG00000095203
Uniprot IDs		Q8N2D6 Q9Y6N6	Q59GC2 Q9H329 Q9NX84
PDB IDs
Enriched GO Terms of Interacting Partners?		Acute-phase Response Blood Microparticle Acute Inflammatory Response Response To Bacterium Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Lipid Storage	Nuclear Body Organization R-loop Processing Nuclear Speck Organization Sequestering Of Calcium Ion Retrograde Protein Transport, ER To Cytosol Actin Rod Assembly Sarcoplasmic Reticulum Lumen Cellular Response To ATP Endoplasmic Reticulum Chaperone Complex Endocytic Vesicle Lumen Response To Manganese Ion Positive Regulation Of Toll-like Receptor Signaling Pathway Sperm Plasma Membrane Protein Folding In Endoplasmic Reticulum Cellular Response To Manganese Ion Astrocyte Development Smooth Endoplasmic Reticulum
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