LAMC3 and CWC25

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		LAMC3	CWC25
Gene Name		laminin, gamma 3	CWC25 spliceosome-associated protein homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Basement Membrane Membrane
	Molecular Function	Structural Molecule Activity
	Biological Process	Cell Morphogenesis Involved In Differentiation Cell Adhesion Visual Perception Astrocyte Development Extracellular Matrix Organization Retina Development In Camera-type Eye
Pathways		Laminin interactions Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: ANXA5 CFB CRP CSNK2A2 CWC25 CYP2E1 EPB41L4B FRAT1 HP KIF1C LGMN NR1H2 PELI2 POT1 RPL35 SERPINA3 SLC43A3 TF YTHDC1 ZNF160	3 interactors: CCDC85B LAMC3 MDM2
Entrez ID		10319	54883
HPRD ID		05069	07892
Ensembl ID		ENSG00000050555	ENSG00000108296
Uniprot IDs		Q8N2D6 Q9Y6N6	Q9NXE8
PDB IDs
Enriched GO Terms of Interacting Partners?		Acute-phase Response Acute Inflammatory Response Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Lipid Storage Regulation Of Protein Processing Defense Response Regulation Of Immune Response Regulation Of Macrophage Derived Foam Cell Differentiation Response To Stress Positive Regulation Of Secretion Of Lysosomal Enzymes Positive Regulation Of Pancreatic Juice Secretion Positive Regulation Of High-density Lipoprotein Particle Assembly Positive Regulation Of DNA Strand Elongation Negative Regulation Of Hydrogen Peroxide Catabolic Process Regulation Of Lipid Storage Regulation Of Innate Immune Response Positive Regulation Of Immune Response Negative Regulation Of Chromosome Organization Regulation Of High-density Lipoprotein Particle Assembly Telomere Formation Via Telomerase Negative Regulation Of Proteolysis Regulation Of Immune System Process Negative Regulation Of Protein Processing Negative Regulation Of Catalytic Activity Negative Regulation Of Pinocytosis Negative Regulation Of Hydrogen Peroxide Metabolic Process	Cellular Response To UV-C Cellular Response To Vitamin B1 Traversing Start Control Point Of Mitotic Cell Cycle Response To Vitamin B1 Response To Ether Response To UV-C Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Export From Nucleus Response To Magnesium Ion Cellular Response To Antibiotic Negative Regulation Of Cell Cycle Arrest Astrocyte Development Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Cellular Response To Toxic Substance Negative Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Cycle G1/S Phase Transition Protein Destabilization Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Cellular Response To Estrogen Stimulus Regulation Of Protein Export From Nucleus Response To Iron Ion Cellular Response To Alkaloid Response To Morphine Astrocyte Differentiation Cellular Response To Nutrient Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Transcription, DNA-templated Response To Cocaine Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Fat Cell Differentiation Response To Antibiotic Cellular Response To Hydrogen Peroxide Signal Transduction Involved In DNA Damage Checkpoint Cellular Response To UV Signal Transduction Involved In Cell Cycle Checkpoint Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Proteasomal Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Negative Regulation Of Biosynthetic Process Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint
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