LAMC3 and SLC43A3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		LAMC3	SLC43A3
Description		laminin subunit gamma 3	solute carrier family 43 member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Membrane Extracellular Matrix	Plasma Membrane Membrane Basolateral Plasma Membrane
	Molecular Function	Structural Molecule Activity	Protein Binding Adenine Transmembrane Transporter Activity Guanine Transmembrane Transporter Activity Fatty Acid Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity
	Biological Process	Cell Morphogenesis Cell Adhesion Visual Perception Astrocyte Development Retina Development In Camera-type Eye	Lipid Transport Adenine Transport Fatty Acid Transport Hypoxanthine Transport Xenobiotic Transport Guanine Transmembrane Transport
Pathways		Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions MET activates PTK2 signaling Attachment of bacteria to epithelial cells Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC) Developmental Lineage of Pancreatic Ductal Cells
Drugs
Diseases
GWAS		Alcohol consumption (max-drinks) ( 29460428) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Degraded stimulus continuous performance test score ( 31596458) Endometriosis ( 28333195) Oral cavity and pharyngeal cancer ( 27749845) Oral cavity cancer ( 27749845) Smoking status (heavy vs never) ( 26423011)	Crohn's disease ( 22412388) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 27863252 32888494) Pursuit maintenance gain ( 29064472)
Interacting Genes		20 interacting genes: ANXA5 CFB CRP CSNK2A2 CWC25 CYP2E1 EPB41L4B FRAT1 HP KIF1C LGMN NR1H2 PELI2 POT1 RPL35 SERPINA3 SLC43A3 TF YTHDC1 ZNF160	2 interacting genes: LAMC3 VCP
Entrez ID		10319	29015
HPRD ID		05069	15391
Ensembl ID		ENSG00000050555	ENSG00000134802
Uniprot IDs		Q8N2D6 Q9Y6N6	B0AZP8 Q8NBI5
PDB IDs
Enriched GO Terms of Interacting Partners?		Acute-phase Response Blood Microparticle Acute Inflammatory Response Response To Bacterium Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Lipid Storage	Flavin Adenine Dinucleotide Catabolic Process VCP-NSFL1C Complex Cellular Response To Arsenite Ion Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Mitotic Spindle Disassembly Positive Regulation Of Oxidative Phosphorylation Positive Regulation Of Protein K63-linked Deubiquitination Cytoplasm Protein Quality Control BAT3 Complex Binding Positive Regulation Of Protein Deubiquitination Positive Regulation Of Mitochondrial Membrane Potential Aggresome Assembly Negative Regulation Of Protein Localization To Chromatin Stress Granule Disassembly Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Deubiquitinase Activator Activity Protein-DNA Covalent Cross-linking Repair Inclusion Body Assembly Derlin-1 Retrotranslocation Complex VCP-NPL4-UFD1 AAA ATPase Complex Regulation Of Protein Localization To Chromatin Regulation Of Protein Deubiquitination Positive Regulation Of Membrane Potential K48-linked Polyubiquitin Modification-dependent Protein Binding ATPase Complex Ubiquitin-modified Protein Reader Activity Cellular Response To Misfolded Protein Positive Regulation Of Cellular Respiration Response To Misfolded Protein Positive Regulation Of ATP Biosynthetic Process Retrograde Protein Transport, ER To Cytosol Cellular Response To Arsenic-containing Substance MHC Class I Protein Binding Astrocyte Development Regulation Of ATP Biosynthetic Process Ubiquitin-specific Protease Binding Viral Genome Replication Regulation Of Oxidative Phosphorylation Translesion Synthesis Negative Regulation Of Hippo Signaling Ubiquitin-like Protein Ligase Binding Regulation Of Aerobic Respiration Cellular Response To Topologically Incorrect Protein Response To Arsenic-containing Substance Protein Exit From Endoplasmic Reticulum Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Postreplication Repair NAD+ Metabolic Process Regulation Of Cellular Respiration Polyubiquitin Modification-dependent Protein Binding
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