YME1L1 and MYOG

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		YME1L1	MYOG
Description		YME1 like 1 ATPase	myogenin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Nuclear Body	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Protein-DNA Complex
	Molecular Function	Nucleotide Binding ATP-dependent Peptidase Activity Metalloendopeptidase Activity Protein Binding ATP Binding Peptidase Activity Metallopeptidase Activity Hydrolase Activity ATP Hydrolysis Activity Metal Ion Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Chromatin DNA Binding Sequence-specific DNA Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Proteolysis Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Mitochondrion Organization Cell Population Proliferation Cellular Response To Starvation Positive Regulation Of Mitochondrial Fusion Protein Hexamerization Mitochondrial Protein Processing Mitochondrial Protein Catabolic Process Negative Regulation Of Apoptotic Process Neuronal Stem Cell Population Maintenance Regulation Of Stem Cell Division	Ossification Regulation Of DNA-templated Transcription Muscle Organ Development Skeletal Muscle Tissue Development Negative Regulation Of Cell Population Proliferation Tissue Development Positive Regulation Of Myotube Differentiation Positive Regulation Of Muscle Atrophy Regulation Of Skeletal Muscle Satellite Cell Proliferation Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Striated Muscle Atrophy Response To Denervation Involved In Regulation Of Muscle Adaptation Myotube Differentiation Cell Differentiation Skeletal Muscle Cell Differentiation Muscle Cell Differentiation Muscle Cell Fate Commitment Positive Regulation Of Myoblast Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Development Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Regulation Of Cell Cycle Cellular Response To Lithium Ion Cellular Response To Tumor Necrosis Factor Cellular Response To Growth Factor Stimulus Cellular Response To Estradiol Stimulus Regulation Of Myoblast Fusion
Pathways		Processing of SMDT1 Mitochondrial protein degradation Cellular response to mitochondrial stress	Myogenesis Myogenesis TGFBR3 expression
Drugs
Diseases
GWAS		Shigella-associated diarrhea ( 33649051) Smoking initiation (ever regular vs never regular) ( 30679032)	Asthma ( 30929738 31959851) Asthma (childhood onset) ( 30929738)
Interacting Genes		7 interacting genes: BCL11A MYOG OGT PSEN1 PSMG1 RNF26 UBC	62 interacting genes: ABI2 BBS4 BFSP2 BHLHA15 CALM1 CALM2 CALM3 CARM1 CCDC120 CCDC28A CDH18 CFAP53 CFTR CLUAP1 CPSF4 CSRP3 CTNNA3 EIF4E2 FAM110A FAM90A1 FBXO32 FBXO7 FIGLA FTL GEM H2AP HNF1A ID1 ID2 ID3 IKBIP IL16 KLHL42 LAMTOR5 LMO3 MAPK3 MAPKBP1 MBD3 MDFI MEF2A MEF2C MLH1 NEK6 ODAD4 PACRGL POLR2C POLR2J PRMT5 SEPTIN5 SP1 SPG21 SRF TAF6L TCF3 TLE5 TRIM43 TSSK3 TTC32 TXNDC9 USHBP1 YME1L1 ZCCHC14
Entrez ID		10730	4656
HPRD ID		06981	01167
Ensembl ID		ENSG00000136758	ENSG00000122180
Uniprot IDs		Q96TA2	P15173
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Oxygen-containing Compound Protein Modification Process Regulation Of ATP Metabolic Process Negative Regulation Of Axonogenesis Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Negative Regulation Of Core Promoter Binding Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Proteasome Core Complex Assembly Negative Regulation Of Branching Morphogenesis Of A Nerve Negative Regulation Of Neuron Remodeling Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Purine Nucleotide Metabolic Process Chromatin DNA Binding Nucleoplasm Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Positive Regulation Of Muscle Atrophy Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Positive Regulation Of Developmental Process Protein Catabolic Process At Postsynapse Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cajal-Retzius Cell Differentiation Proteolysis Negative Regulation Of Transcription Regulatory Region DNA Binding Negative Regulation Of Neuron Projection Development Regulation Of Generation Of Precursor Metabolites And Energy Negative Regulation Of Neurogenesis Negative Regulation Of Protein-containing Complex Assembly Protein O-acetylglucosaminyltransferase Activity Negative Regulation Of Protein Homooligomerization Transcription Regulatory Region Nucleic Acid Binding Negative Regulation Of Neuron Maturation Positive Regulation Of L-glutamate Import Across Plasma Membrane Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Axonogenesis Synaptic Vesicle Targeting Protein Glycosylation Negative Regulation Of Nervous System Development Negative Regulation Of Proteolysis Macromolecule Glycosylation Astrocyte Activation Involved In Immune Response Negative Regulation Of Dendrite Extension Negative Regulation Of Protein Oligomerization Regulation Of Multicellular Organismal Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Multicellular Organismal Process Positive Regulation Of DNA-templated Transcription Sequestering Of Calcium Ion	Protein Dimerization Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity DNA-binding Transcription Factor Binding Cytoskeleton Transporter Inhibitor Activity Regulation Of Calcium Ion Export Across Plasma Membrane Spindle Pole Protein-containing Complex BHLH Transcription Factor Binding Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Heart Development Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of High Voltage-gated Calcium Channel Activity Titin Binding Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Transcription Regulator Inhibitor Activity Spindle Microtubule Nucleus Detection Of Calcium Ion Cardiac Myofibril Assembly Regulation Of Cell Communication By Electrical Coupling Calcium Channel Regulator Activity Protein Phosphatase Activator Activity Protein Heterodimerization Activity Histone Arginine N-methyltransferase Activity Calyx Of Held Sarcomere E-box Binding Positive Regulation Of Macromolecule Biosynthetic Process Face Development Catalytic Complex Heart Looping Regulation Of Developmental Process Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Heart Contraction Developmental Process Embryonic Heart Tube Morphogenesis Negative Regulation Of Transporter Activity Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium Channel Complex Calcineurin-mediated Signaling Positive Regulation Of Biosynthetic Process Lung Morphogenesis Regulation Of B Cell Activation Presynaptic Cytosol Regulation Of Cardiac Muscle Cell Action Potential Response To Calcium Ion Myelin Sheath
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