MYOG and ID3

Number of citations of the paper that reports this interaction (PMID 9242638)
48

Data Source:
HPRD (two hybrid)

		MYOG	ID3
Gene Name		myogenin (myogenic factor 4)	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Protein-DNA Complex	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Core Promoter Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Chromatin DNA Binding Sequence-specific DNA Binding Protein Heterodimerization Activity E-box Binding	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding Protein Dimerization Activity
	Biological Process	Ossification Cell Cycle Skeletal Muscle Tissue Development Negative Regulation Of Cell Proliferation Positive Regulation Of Myotube Differentiation Positive Regulation Of Muscle Atrophy Regulation Of Satellite Cell Proliferation Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Striated Muscle Atrophy Response To Denervation Involved In Regulation Of Muscle Adaptation Skeletal Muscle Cell Differentiation Muscle Cell Differentiation Muscle Cell Fate Commitment MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Muscle Cell Differentiation Positive Regulation Of Cell Cycle Arrest Cellular Response To Lithium Ion Cellular Response To Growth Factor Stimulus Cellular Response To Estradiol Stimulus Regulation Of Myoblast Fusion Positive Regulation Of Myoblast Fusion	Negative Regulation Of Transcription From RNA Polymerase II Promoter Metanephros Development Regulation Of DNA Replication Transcription, DNA-templated Multicellular Organismal Development Central Nervous System Development Heart Development Muscle Organ Development Circadian Rhythm Response To Wounding Neuron Differentiation Epithelial Cell Differentiation Notochord Development Odontogenesis Positive Regulation Of Apoptotic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Myoblast Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle
Pathways		CDO in myogenesis Myogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: BBS4 CALM1 CALM2 CALM3 CARM1 CCDC28A CDH18 CLUAP1 CSRP3 EIF4E2 ELSPBP1 FTL HYPM ID1 ID2 ID3 IKBIP MAPK3 MDFI MEF2A MEF2C MLH1 NF1 PACRGL POLR2C PRMT5 SEPT5 SP1 SRF TAF6L TCF3 TRIM43 TTC25 TXNDC9 YME1L1	36 interactors: ADD1 ATF3 CBFA2T2 CDK2 CNOT3 CSK E2F4 ELK1 ELK4 FAM74A1 FHL2 GATA4 GNB2 GTF2A1L HES1 ID4 IFI16 IKBKG MLX MYF5 MYF6 MYOD1 MYOG PAX5 PRDM14 PUF60 RND1 RUNX1T1 SAP30 SREBF1 TCF12 TCF3 TCF4 ZNF3 ZNF408 ZNF626
Entrez ID		4656	3399
HPRD ID		01167	02608
Ensembl ID		ENSG00000122180	ENSG00000117318
Uniprot IDs		P15173	Q02535
PDB IDs			2LFH
Enriched GO Terms of Interacting Partners?		Cell Activation Positive Regulation Of Phosphatase Activity Heart Development Organ Morphogenesis Positive Regulation Of Dephosphorylation Anatomical Structure Development Organ Development Cardiac Myofibril Assembly Determination Of Heart Left/right Asymmetry Positive Regulation Of Cellular Biosynthetic Process Regulation Of Binding Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Anatomical Structure Morphogenesis Regulation Of Heart Contraction Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Cellular Metabolic Process Developmental Process Cardiovascular System Development Embryo Development Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Organ Development Embryonic Organ Morphogenesis Positive Regulation Of Adenylate Cyclase Activity Negative Regulation Of Binding Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Phosphatase Activity Organelle Organization System Development Determination Of Left/right Symmetry Multicellular Organismal Development Neurotrophin TRK Receptor Signaling Pathway Determination Of Bilateral Symmetry Neurotrophin Signaling Pathway Response To Calcium Ion Positive Regulation Of Lyase Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Response To Growth Factor Stimulus Tissue Development Regulation Of Osteoblast Differentiation Response To Growth Factor Regulation Of Dephosphorylation Detection Of Calcium Ion Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Communication By Electrical Coupling Regulation Of Adenylate Cyclase Activity Muscle System Process Cell Development	Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Muscle Structure Development Skeletal Muscle Cell Differentiation Positive Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Developmental Process Regulation Of Cellular Process Positive Regulation Of Skeletal Muscle Fiber Development Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Cell Fate Commitment Negative Regulation Of Transcription From RNA Polymerase II Promoter Striated Muscle Tissue Development Multicellular Organismal Development Muscle Cell Differentiation Muscle Tissue Development Negative Regulation Of Cellular Metabolic Process Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Organ Development
Tagcloud ?		boxes c2c12 c3h10t1 cardiotoxin colocalized dux4 duxbl dystrophy elongated embryogenesis facioscapulohumeral fshd homeobox homeodomain hyper multipotent muscles myoblast myocytes myod myogenesis myogenic myotubes organogenesis overexpressions quiescent regenerated satellite trunk	accumulating associates box compartment competition constitute developmentally e2a e47 enforced erythroid gal helix heterodimers hypermethylation implicates k562 lineages lymphoid metazoa overlapping shift specificities strict suggestive tal1 vicinity vp16
Tagcloud (Difference) ?		boxes c2c12 c3h10t1 cardiotoxin colocalized dux4 duxbl dystrophy elongated embryogenesis facioscapulohumeral fshd homeobox homeodomain hyper multipotent muscles myoblast myocytes myod myogenesis myogenic myotubes organogenesis overexpressions quiescent regenerated satellite trunk	accumulating associates box compartment competition constitute developmentally e2a e47 enforced erythroid gal helix heterodimers hypermethylation implicates k562 lineages lymphoid metazoa overlapping shift specificities strict suggestive tal1 vicinity vp16
Tagcloud (Intersection) ?