MYOG and CDH18

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		MYOG	CDH18
Gene Name		myogenin (myogenic factor 4)	cadherin 18, type 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Protein-DNA Complex	Plasma Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Core Promoter Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Chromatin DNA Binding Sequence-specific DNA Binding Protein Heterodimerization Activity E-box Binding	Calcium Ion Binding
	Biological Process	Ossification Cell Cycle Skeletal Muscle Tissue Development Negative Regulation Of Cell Proliferation Positive Regulation Of Myotube Differentiation Positive Regulation Of Muscle Atrophy Regulation Of Satellite Cell Proliferation Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Striated Muscle Atrophy Response To Denervation Involved In Regulation Of Muscle Adaptation Skeletal Muscle Cell Differentiation Muscle Cell Differentiation Muscle Cell Fate Commitment MRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Muscle Cell Differentiation Positive Regulation Of Cell Cycle Arrest Cellular Response To Lithium Ion Cellular Response To Growth Factor Stimulus Cellular Response To Estradiol Stimulus Regulation Of Myoblast Fusion Positive Regulation Of Myoblast Fusion	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell Junction Assembly Adherens Junction Organization Cell-cell Junction Organization
Pathways		CDO in myogenesis Myogenesis	Cell junction organization Cell-cell junction organization Adherens junctions interactions
Drugs
Diseases
GWAS			Depression (quantitative trait) ( 20800221)
Protein-Protein Interactions		35 interactors: BBS4 CALM1 CALM2 CALM3 CARM1 CCDC28A CDH18 CLUAP1 CSRP3 EIF4E2 ELSPBP1 FTL HYPM ID1 ID2 ID3 IKBIP MAPK3 MDFI MEF2A MEF2C MLH1 NF1 PACRGL POLR2C PRMT5 SEPT5 SP1 SRF TAF6L TCF3 TRIM43 TTC25 TXNDC9 YME1L1	4 interactors: CDH12 CDH6 CDH9 MYOG
Entrez ID		4656	1016
HPRD ID		01167	04314
Ensembl ID		ENSG00000122180	ENSG00000145526
Uniprot IDs		P15173	D6RER2 Q13634
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Activation Positive Regulation Of Phosphatase Activity Heart Development Organ Morphogenesis Positive Regulation Of Dephosphorylation Anatomical Structure Development Organ Development Cardiac Myofibril Assembly Determination Of Heart Left/right Asymmetry Positive Regulation Of Cellular Biosynthetic Process Regulation Of Binding Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Anatomical Structure Morphogenesis Regulation Of Heart Contraction Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Cellular Metabolic Process Developmental Process Cardiovascular System Development Embryo Development Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Organ Development Embryonic Organ Morphogenesis Positive Regulation Of Adenylate Cyclase Activity Negative Regulation Of Binding Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Phosphatase Activity Organelle Organization System Development Determination Of Left/right Symmetry Multicellular Organismal Development Neurotrophin TRK Receptor Signaling Pathway Determination Of Bilateral Symmetry Neurotrophin Signaling Pathway Response To Calcium Ion Positive Regulation Of Lyase Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Response To Growth Factor Stimulus Tissue Development Regulation Of Osteoblast Differentiation Response To Growth Factor Regulation Of Dephosphorylation Detection Of Calcium Ion Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Communication By Electrical Coupling Regulation Of Adenylate Cyclase Activity Muscle System Process Cell Development	Adherens Junction Organization Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell Junction Assembly Cell-cell Junction Organization Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Positive Regulation Of Muscle Atrophy Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Cell Adhesion Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Positive Regulation Of Skeletal Muscle Fiber Development Striated Muscle Atrophy Muscle Atrophy Regulation Of Satellite Cell Proliferation Response To Denervation Involved In Regulation Of Muscle Adaptation Response To Inactivity Cellular Component Assembly MRNA Transcription From RNA Polymerase II Promoter Response To Muscle Activity MRNA Transcription Cellular Response To Lithium Ion Muscle Cell Fate Commitment Positive Regulation Of Myoblast Differentiation Positive Regulation Of Myoblast Fusion Cellular Response To Estradiol Stimulus Regulation Of Skeletal Muscle Fiber Development Regulation Of Myoblast Fusion Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Tissue Development Cellular Response To Estrogen Stimulus Myotube Cell Development Response To Lithium Ion Positive Regulation Of Myotube Differentiation Regulation Of Myoblast Differentiation Response To Electrical Stimulus Muscle Fiber Development Response To Activity Myotube Differentiation Regulation Of Myotube Differentiation Skeletal Muscle Cell Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Striated Muscle Tissue Development Positive Regulation Of Muscle Tissue Development Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Muscle Cell Differentiation Regulation Of Striated Muscle Cell Differentiation Regulation Of Cell Cycle Arrest
Tagcloud ?		boxes c2c12 c3h10t1 cardiotoxin colocalized dux4 duxbl dystrophy elongated embryogenesis facioscapulohumeral fshd homeobox homeodomain hyper multipotent muscles myoblast myocytes myod myogenesis myogenic myotubes organogenesis overexpressions quiescent regenerated satellite trunk
Tagcloud (Difference) ?		boxes c2c12 c3h10t1 cardiotoxin colocalized dux4 duxbl dystrophy elongated embryogenesis facioscapulohumeral fshd homeobox homeodomain hyper multipotent muscles myoblast myocytes myod myogenesis myogenic myotubes organogenesis overexpressions quiescent regenerated satellite trunk
Tagcloud (Intersection) ?