MYOG and CLUAP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MYOG	CLUAP1
Description		myogenin	clusterin associated protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Protein-DNA Complex	Nucleus Nucleoplasm Centrosome Microtubule Organizing Center Cilium Actin Cytoskeleton Intraciliary Transport Particle A Intraciliary Transport Particle B Cell Projection Ciliary Tip Ciliary Base
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Chromatin DNA Binding Sequence-specific DNA Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Ossification Regulation Of DNA-templated Transcription Muscle Organ Development Skeletal Muscle Tissue Development Negative Regulation Of Cell Population Proliferation Tissue Development Positive Regulation Of Myotube Differentiation Positive Regulation Of Muscle Atrophy Regulation Of Skeletal Muscle Satellite Cell Proliferation Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Striated Muscle Atrophy Response To Denervation Involved In Regulation Of Muscle Adaptation Myotube Differentiation Cell Differentiation Skeletal Muscle Cell Differentiation Muscle Cell Differentiation Muscle Cell Fate Commitment Positive Regulation Of Myoblast Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Development Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Regulation Of Cell Cycle Cellular Response To Lithium Ion Cellular Response To Tumor Necrosis Factor Cellular Response To Growth Factor Stimulus Cellular Response To Estradiol Stimulus Regulation Of Myoblast Fusion	Neural Tube Closure Heart Looping Smoothened Signaling Pathway Floor Plate Formation Cell Projection Organization Axoneme Assembly Intraciliary Anterograde Transport Cilium Assembly Left/right Pattern Formation
Pathways		Myogenesis Myogenesis TGFBR3 expression	Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Asthma ( 30929738 31959851) Asthma (childhood onset) ( 30929738)	Cerebrospinal fluid α-synuclein levels ( 29959729) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Type 2 diabetes ( 30297969)
Interacting Genes		62 interacting genes: ABI2 BBS4 BFSP2 BHLHA15 CALM1 CALM2 CALM3 CARM1 CCDC120 CCDC28A CDH18 CFAP53 CFTR CLUAP1 CPSF4 CSRP3 CTNNA3 EIF4E2 FAM110A FAM90A1 FBXO32 FBXO7 FIGLA FTL GEM H2AP HNF1A ID1 ID2 ID3 IKBIP IL16 KLHL42 LAMTOR5 LMO3 MAPK3 MAPKBP1 MBD3 MDFI MEF2A MEF2C MLH1 NEK6 ODAD4 PACRGL POLR2C POLR2J PRMT5 SEPTIN5 SP1 SPG21 SRF TAF6L TCF3 TLE5 TRIM43 TSSK3 TTC32 TXNDC9 USHBP1 YME1L1 ZCCHC14	7 interacting genes: APP CINP CLU MAGEA11 MYOG UBXN10 VCP
Entrez ID		4656	23059
HPRD ID		01167	10013
Ensembl ID		ENSG00000122180	ENSG00000103351
Uniprot IDs		P15173	J3KNW5 Q96AJ1
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Dimerization Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity DNA-binding Transcription Factor Binding Cytoskeleton Transporter Inhibitor Activity Regulation Of Calcium Ion Export Across Plasma Membrane Spindle Pole Protein-containing Complex BHLH Transcription Factor Binding Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Heart Development Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of High Voltage-gated Calcium Channel Activity Titin Binding Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Transcription Regulator Inhibitor Activity Spindle Microtubule Nucleus Detection Of Calcium Ion Cardiac Myofibril Assembly Regulation Of Cell Communication By Electrical Coupling Calcium Channel Regulator Activity Protein Phosphatase Activator Activity Protein Heterodimerization Activity Histone Arginine N-methyltransferase Activity Calyx Of Held Sarcomere E-box Binding Positive Regulation Of Macromolecule Biosynthetic Process Face Development Catalytic Complex Heart Looping Regulation Of Developmental Process Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Heart Contraction Developmental Process Embryonic Heart Tube Morphogenesis Negative Regulation Of Transporter Activity Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium Channel Complex Calcineurin-mediated Signaling Positive Regulation Of Biosynthetic Process Lung Morphogenesis Regulation Of B Cell Activation Presynaptic Cytosol Regulation Of Cardiac Muscle Cell Action Potential Response To Calcium Ion Myelin Sheath	Positive Regulation Of Amyloid Fibril Formation Response To Misfolded Protein Regulation Of Amyloid Fibril Formation Regulation Of Amyloid-beta Clearance Positive Regulation Of Proteolysis Low-density Lipoprotein Particle Receptor Binding Positive Regulation Of Protein Catabolic Process Microglial Cell Activation Positive Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of ATP Metabolic Process Leukocyte Activation Involved In Inflammatory Response Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Receptor-mediated Endocytosis Amyloid-beta Complex Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Response To Calcium Ion Platelet Alpha Granule Lumen Macrophage Activation Amylin Binding Regulation Of Proteolysis Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Catabolic Process Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Nitric Oxide Metabolic Process Perinuclear Endoplasmic Reticulum Lumen Regulation Of Neuronal Signal Transduction Flavin Adenine Dinucleotide Catabolic Process Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Tumor Necrosis Factor Production Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Receptor-mediated Endocytosis Regulation Of Response To Endoplasmic Reticulum Stress Receptor Ligand Activity Lipoprotein Particle Myeloid Leukocyte Activation Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
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