CFL2 and DSTN

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CFL2	DSTN
Gene Name		cofilin 2 (muscle)	destrin (actin depolymerizing factor)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Actin Cytoskeleton Nuclear Matrix I Band Extracellular Vesicular Exosome	Actin Cytoskeleton Cortical Actin Cytoskeleton Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Protein Binding	Actin Binding
	Biological Process	Actin Filament Depolymerization Positive Regulation Of Actin Filament Depolymerization Sarcomere Organization Muscle Cell Cellular Homeostasis Regulation Of Dendritic Spine Morphogenesis	Movement Of Cell Or Subcellular Component Actin Polymerization Or Depolymerization Actin Filament Depolymerization Positive Regulation Of Actin Filament Depolymerization Actin Filament Severing
Pathways
Drugs
Diseases
GWAS			Presence of antiphospholipid antibodies ( 23509613)
Protein-Protein Interactions		8 interactors: ACTB ACTG1 CAP2 CFL1 DSTN LIMK1 POT1 SSH1	8 interactors: ACTB ACTG1 CFL2 SHBG SMAD9 SSH1 TAX1BP1 TESK2
Entrez ID		1073	11034
HPRD ID		03262	16446
Ensembl ID		ENSG00000165410	ENSG00000125868
Uniprot IDs		Q549N0 Q9Y281	P60981
PDB IDs
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Axon Guidance Organelle Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cell Morphogenesis Axonogenesis Cytoskeleton Organization Axon Development Cell Morphogenesis Involved In Neuron Differentiation Actin Cytoskeleton Organization Chemotaxis Actin Filament-based Process Neuron Projection Morphogenesis Phagocytosis Fc Receptor Signaling Pathway Cell Morphogenesis Involved In Differentiation Immune Response-activating Cell Surface Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Generation Of Neurons Positive Regulation Of Actin Filament Depolymerization Regulation Of Cellular Component Size Neuron Projection Development Cell Projection Morphogenesis Neurogenesis Cell Part Morphogenesis Regulation Of Actin Cytoskeleton Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Organelle Organization Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Neuron Development Positive Regulation Of Protein Depolymerization Actin Filament Depolymerization Immune Response-regulating Signaling Pathway Neuron Differentiation Regulation Of Cytoskeleton Organization Cell Projection Organization Nervous System Development Locomotion Anatomical Structure Morphogenesis Positive Regulation Of Protein Complex Disassembly Platelet Activation Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Immune Response Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway	Adherens Junction Organization Actin Cytoskeleton Organization Cell Junction Assembly Actin Filament-based Process Cell-cell Junction Organization Platelet Aggregation Sarcomere Organization Retina Homeostasis Myofibril Assembly Cytoskeleton Organization Primary Spermatocyte Growth Midbrain Development Nervous System Development Ephrin Receptor Signaling Pathway Anatomical Structure Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Actomyosin Structure Organization Generation Of Neurons Striated Muscle Cell Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Neurogenesis Muscle Cell Development Anatomical Structure Development Tissue Homeostasis Organelle Organization Platelet Activation Cell Development Innate Immune Response Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Cellular Component Assembly Cell Differentiation Striated Muscle Cell Differentiation Mullerian Duct Regression Enzyme Linked Receptor Protein Signaling Pathway Multicellular Organismal Homeostasis Developmental Process Cellular Response To ATP Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Morphogenesis Positive Regulation Of Actin Filament Depolymerization Muscle Cell Differentiation Regulation Of Cellular Component Size Homotypic Cell-cell Adhesion System Development Single Organism Reproductive Process
Tagcloud ?		adipogenesis adipogenic adipose ankrd1 ankyrin bovine bulls cofilin dehydrogenase differentially hspb1 lactate ldhb likewise mlc1 monitored myogenesis myogenic myosin repeat skeletal steers taldo1 tenfold testosterone threefold transaldolase twofold vary
Tagcloud (Difference) ?		adipogenesis adipogenic adipose ankrd1 ankyrin bovine bulls cofilin dehydrogenase differentially hspb1 lactate ldhb likewise mlc1 monitored myogenesis myogenic myosin repeat skeletal steers taldo1 tenfold testosterone threefold transaldolase twofold vary
Tagcloud (Intersection) ?