CTCF and ZMYM4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CTCF	ZMYM4
Gene Name		CCCTC-binding factor (zinc finger protein)	zinc finger, MYM-type 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Condensed Chromosome Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Chromatin Insulator Sequence Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding	DNA Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation Regulation Of Gene Expression By Genetic Imprinting Transcription, DNA-templated Chromosome Segregation Maintenance Of DNA Methylation Positive Regulation Of Gene Expression Chromatin Modification Nucleosome Positioning Regulation Of Histone Methylation Regulation Of Histone Acetylation Regulation Of Gene Expression, Epigenetic Regulation Of Molecular Function, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Centromeric Sister Chromatid Cohesion	Cytoskeleton Organization Multicellular Organismal Development Regulation Of Cell Morphogenesis
Pathways
Drugs
Diseases
GWAS		HDL cholesterol ( 19060911)
Protein-Protein Interactions		13 interactors: CHD7 CHD8 HMGB1 POLR2A RXRA SIN3A SMAD3 SMAD4 SUZ12 THRB TRB YBX1 ZMYM4	6 interactors: CTCF FHL2 HIST3H3 ROR2 RUNX1T1 UBQLN1
Entrez ID		10664	9202
HPRD ID		05005	10326
Ensembl ID		ENSG00000102974	ENSG00000146463
Uniprot IDs		P49711	Q5VZL5
PDB IDs		1X6H 2CT1
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process In Utero Embryonic Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Embryo Development Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Developmental Process Nitrogen Compound Metabolic Process Heart Morphogenesis Positive Regulation Of Metabolic Process Multicellular Organismal Development Biosynthetic Process SMAD Protein Complex Assembly Regulation Of Binding Anatomical Structure Development Chromatin Modification Regulation Of Transforming Growth Factor Beta2 Production Tube Development Chromatin Organization	Regulation Of Molecular Function, Epigenetic Atrial Cardiac Muscle Cell Development Wnt Signaling Pathway, Calcium Modulating Pathway Nucleosome Positioning Embryonic Genitalia Morphogenesis Negative Regulation Of Transcription, DNA-templated Maintenance Of DNA Methylation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Centromeric Sister Chromatid Cohesion Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Heart Trabecula Formation Regulation Of Sister Chromatid Cohesion Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Ventricular Cardiac Muscle Cell Development Genitalia Morphogenesis Positive Regulation Of Cellular Biosynthetic Process Wnt Signaling Pathway, Planar Cell Polarity Pathway Cartilage Condensation Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Heart Trabecula Morphogenesis Regulation Of Gene Expression By Genetic Imprinting Ventricular Cardiac Muscle Cell Differentiation Non-canonical Wnt Signaling Pathway Genetic Imprinting Androgen Receptor Signaling Pathway
Tagcloud ?		acting angle bend bending binds chicken confer direction efficiently erba f1 f2 fails flexure hetero heterodimer homodimer homologue lysozyme magnitude nep1 quaternary represses rxr silencer simultaneously synergistically t3 tr
Tagcloud (Difference) ?		acting angle bend bending binds chicken confer direction efficiently erba f1 f2 fails flexure hetero heterodimer homodimer homologue lysozyme magnitude nep1 quaternary represses rxr silencer simultaneously synergistically t3 tr
Tagcloud (Intersection) ?