ZMYM4 and ROR2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZMYM4	ROR2
Gene Name		zinc finger, MYM-type 4	receptor tyrosine kinase-like orphan receptor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane Clathrin-coated Endocytic Vesicle Membrane
	Molecular Function	DNA Binding Zinc Ion Binding	Transmembrane Receptor Protein Tyrosine Kinase Activity Frizzled Binding Protein Binding ATP Binding Wnt-protein Binding
	Biological Process	Cytoskeleton Organization Multicellular Organismal Development Regulation Of Cell Morphogenesis	Cartilage Condensation Somitogenesis Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Wnt Signaling Pathway, Calcium Modulating Pathway JNK Cascade Multicellular Organismal Development Negative Regulation Of Cell Proliferation Peptidyl-tyrosine Phosphorylation Cell Differentiation Positive Regulation Of Cell Migration Embryonic Genitalia Morphogenesis Inner Ear Morphogenesis Positive Regulation Of Transcription, DNA-templated Wnt Signaling Pathway, Planar Cell Polarity Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways			WNT5A-dependent internalization of FZD2, FZD5 and ROR2 Signaling by Wnt PCP/CE pathway beta-catenin independent WNT signaling
Drugs
Diseases
GWAS			Bipolar disorder and schizophrenia ( 22688191)
Protein-Protein Interactions		6 interactors: CTCF FHL2 HIST3H3 ROR2 RUNX1T1 UBQLN1	13 interactors: C1orf94 CRX DAB1 DAZAP2 FZD2 FZD5 IKBKG MAGED1 MAP3K7 PRR20A RBPMS WNT5A ZMYM4
Entrez ID		9202	4920
HPRD ID		10326	03822
Ensembl ID		ENSG00000146463	ENSG00000169071
Uniprot IDs		Q5VZL5	Q01974
PDB IDs			3ZZW 4GT4
Enriched GO Terms of Interacting Partners?		Regulation Of Molecular Function, Epigenetic Atrial Cardiac Muscle Cell Development Wnt Signaling Pathway, Calcium Modulating Pathway Nucleosome Positioning Embryonic Genitalia Morphogenesis Negative Regulation Of Transcription, DNA-templated Maintenance Of DNA Methylation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Centromeric Sister Chromatid Cohesion Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Heart Trabecula Formation Regulation Of Sister Chromatid Cohesion Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Ventricular Cardiac Muscle Cell Development Genitalia Morphogenesis Positive Regulation Of Cellular Biosynthetic Process Wnt Signaling Pathway, Planar Cell Polarity Pathway Cartilage Condensation Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Heart Trabecula Morphogenesis Regulation Of Gene Expression By Genetic Imprinting Ventricular Cardiac Muscle Cell Differentiation Non-canonical Wnt Signaling Pathway Genetic Imprinting Androgen Receptor Signaling Pathway	Positive Regulation Of Protein Phosphorylation Positive Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Kinase Activity Positive Regulation Of Protein Modification Process Positive Regulation Of MAP Kinase Activity Positive Regulation Of Kinase Activity Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of MAP Kinase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Regulation Of Protein Kinase Activity Positive Regulation Of Metabolic Process Non-canonical Wnt Signaling Pathway Regulation Of Kinase Activity Positive Regulation Of MAPK Cascade Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Signal Transduction Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Regulation Of Signaling Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity Positive Regulation Of Transcription, DNA-templated Regulation Of Protein Metabolic Process JNK Cascade Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Canonical Wnt Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cytokine Production Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Gene Expression Planar Cell Polarity Pathway Involved In Neural Tube Closure Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of JNK Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Regulation Of Intracellular Signal Transduction Anterior/posterior Axis Specification, Embryo
Tagcloud ?			alkaline alpi apical apicobasal applying border brush cathode coordinating created cue cytoskeleton determines electric electrical enterocytes erk1 ezrin faces lkb1 lumen mimic orienting polarity polarized polarizing remodeled stk11 transepithelial
Tagcloud (Difference) ?			alkaline alpi apical apicobasal applying border brush cathode coordinating created cue cytoskeleton determines electric electrical enterocytes erk1 ezrin faces lkb1 lumen mimic orienting polarity polarized polarizing remodeled stk11 transepithelial
Tagcloud (Intersection) ?