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CTCF
Gene Name
CCCTC-binding factor (zinc finger protein)
Image
Gene Ontology Annotations
Cellular Component
Chromosome, Centromeric Region
Condensed Chromosome
Nucleus
Nucleoplasm
Nucleolus
Molecular Function
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
Sequence-specific DNA Binding Transcription Factor Activity
Transcription Corepressor Activity
Protein Binding
Zinc Ion Binding
Chromatin Insulator Sequence Binding
Sequence-specific DNA Binding
Transcription Regulatory Region DNA Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
DNA Methylation
Regulation Of Gene Expression By Genetic Imprinting
Transcription, DNA-templated
Chromosome Segregation
Maintenance Of DNA Methylation
Positive Regulation Of Gene Expression
Chromatin Modification
Nucleosome Positioning
Regulation Of Histone Methylation
Regulation Of Histone Acetylation
Regulation Of Gene Expression, Epigenetic
Regulation Of Molecular Function, Epigenetic
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Regulation Of Centromeric Sister Chromatid Cohesion
Pathways
Drugs
Diseases
GWAS
HDL cholesterol (
19060911
)
Protein-protein Interactions
13 interactors:
CHD7
CHD8
HMGB1
POLR2A
RXRA
SIN3A
SMAD3
SMAD4
SUZ12
THRB
TRB
YBX1
ZMYM4
Entrez ID
10664
HPRD ID
05005
Ensembl ID
ENSG00000102974
Uniprot IDs
P49711
PDB IDs
1X6H
2CT1
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
In Utero Embryonic Development
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Biosynthetic Process
RNA Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Chordate Embryonic Development
Embryo Development Ending In Birth Or Egg Hatching
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Transcription From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Gene Expression
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Embryo Development
Cellular Nitrogen Compound Metabolic Process
Macromolecule Biosynthetic Process
Developmental Process
Nitrogen Compound Metabolic Process
Heart Morphogenesis
Positive Regulation Of Metabolic Process
Multicellular Organismal Development
Biosynthetic Process
SMAD Protein Complex Assembly
Regulation Of Binding
Anatomical Structure Development
Chromatin Modification
Regulation Of Transforming Growth Factor Beta2 Production
Tube Development
Chromatin Organization
Tagcloud
?
acting
angle
bend
bending
binds
chicken
confer
direction
efficiently
erba
f1
f2
fails
flexure
hetero
heterodimer
homodimer
homologue
lysozyme
magnitude
nep1
quaternary
represses
rxr
silencer
simultaneously
synergistically
t3
tr