PPP1R9B and CCKAR

Number of citations of the paper that reports this interaction (PubMedID 17464283)
34

Data Source:
HPRD (in vitro)

		PPP1R9B	CCKAR
Description		protein phosphatase 1 regulatory subunit 9B	cholecystokinin A receptor
Image		No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 1 Complex Nucleus Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Adherens Junction Postsynaptic Density Actin Cytoskeleton Membrane Lamellipodium Filopodium Dendrite Growth Cone Cortical Actin Cytoskeleton Ruffle Membrane Dendritic Spine Membrane Cell Projection Neuronal Cell Body Dendritic Spine Dendritic Spine Neck Dendritic Spine Head Synapse Anchoring Junction Spine Apparatus Extrinsic Component Of Postsynaptic Membrane Glutamatergic Synapse Plasma Membrane Bounded Cell Projection Cytoplasmic Side Of Dendritic Spine Plasma Membrane	Nucleoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Actin Binding Protein Kinase Activity Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Kinase Binding D2 Dopamine Receptor Binding Transmembrane Transporter Binding Protein-containing Complex Binding Actin Filament Binding	G Protein-coupled Receptor Activity Cholecystokinin Receptor Activity Peptide Hormone Binding
	Biological Process	Regulation Of Cell Growth By Extracellular Stimulus Response To Amphetamine Developmental Process Involved In Reproduction Actin Filament Organization Regulation Of Exit From Mitosis Nervous System Development Learning RNA Splicing Response To Xenobiotic Stimulus Dendrite Development Cell Migration Calcium-mediated Signaling Hippocampus Development Cerebral Cortex Development Actin Filament Depolymerization Cell Differentiation Negative Regulation Of Cell Growth Neuron Projection Development Response To Estradiol Response To Prostaglandin E Response To Nicotine Response To Immobilization Stress Regulation Of Cell Population Proliferation Response To Amino Acid Filopodium Assembly Response To Steroid Hormone Regulation Of Cell Cycle Male Mating Behavior Reproductive System Development Cellular Response To Morphine Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Xenobiotic Stimulus Regulation Of Postsynapse Assembly Cellular Response To Peptide Positive Regulation Of Protein Localization To Plasma Membrane Protein Localization To Actin Cytoskeleton Positive Regulation Of Protein Localization Positive Regulation Of Protein Localization To Actin Cortical Patch Response To Kainic Acid Response To L-phenylalanine Derivative Protein Localization To Cell Periphery Regulation Of Opioid Receptor Signaling Pathway	Neuron Migration Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Axonogenesis Forebrain Development Cellular Response To Hormone Stimulus Cholecystokinin Signaling Pathway Regulation Of Hormone Secretion
Pathways			Peptide ligand-binding receptors G alpha (q) signalling events
Drugs			Ceruletide Dexloxiglumide Lintitript Cholecystokinin
Diseases
GWAS		Platelet distribution width ( 32888494) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		29 interacting genes: ACTA1 ACTN2 ADRA1A ADRA1B ADRA2A ADRA2B ADRA2C CCKAR CCKBR CDKN2A CHRM3 DCX DRD2 ITGB8 LRRC7 MAPK1 MECOM PPP1CA PPP1R2 PPP1R9A PRKACA RB1 RBL1 RBL2 RGS2 RPS6KB1 SHANK3 TGOLN2 TIAM1	3 interacting genes: CCK CCKBR PPP1R9B
Entrez ID		84687	886
HPRD ID		04506	00322
Ensembl ID		ENSG00000108819	ENSG00000163394
Uniprot IDs		Q96SB3	P32238
PDB IDs			1D6G 1HZN 7EZH 7EZK 7EZM 7F8U 7F8X 7F8Y 7MBX 7MBY 7XOU 7XOV 9BKJ 9BKK
Enriched GO Terms of Interacting Partners?		Adrenergic Receptor Activity Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adrenergic Receptor Signaling Pathway Regulation Of Muscle Contraction Regulation Of Smooth Muscle Contraction Negative Regulation Of Catecholamine Secretion Alpha2-adrenergic Receptor Activity Regulation Of Muscle System Process Intracellular Signaling Cassette Regulation Of Blood Circulation G Protein-coupled Receptor Activity Signal Transduction Regulation Of System Process Regulation Of Cell Communication Regulation Of Signaling Regulation Of Lipid Kinase Activity Intracellular Signal Transduction Negative Regulation Of Epinephrine Secretion Regulation Of Vasoconstriction Negative Regulation Of Norepinephrine Secretion Epinephrine Binding Regulation Of Amine Transport System Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Catecholamine Secretion Regulation Of Biological Quality Regulation Of MAPK Cascade Regulation Of Signal Transduction Regulation Of Norepinephrine Secretion Modulation Of Chemical Synaptic Transmission Positive Regulation Of Muscle Contraction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Developmental Process Phospholipase C-activating Adrenergic Receptor Signaling Pathway Cholecystokinin Receptor Activity Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Hormone Secretion Dendritic Spine Positive Regulation Of Signal Transduction Regulation Of Tube Size Blood Vessel Diameter Maintenance Regulation Of Intracellular Signal Transduction Alpha1-adrenergic Receptor Activity Cholecystokinin Signaling Pathway Regulation Of Insulin Secretion ERBB Signaling Pathway Positive Regulation Of Cellular Component Organization	Cholecystokinin Signaling Pathway Type B Gastrin/cholecystokinin Receptor Binding Gastrin Receptor Activity Positive Regulation Of Ephrin Receptor Signaling Pathway Arterial Endothelial Cell Fate Commitment Positive Regulation Of Protein Localization To Actin Cortical Patch Dendritic Spine Neck Cytoplasmic Side Of Dendritic Spine Plasma Membrane Cholecystokinin Receptor Activity MAML1-RBP-Jkappa- ICN1 Complex Endocardium Morphogenesis Blood Vessel Endothelial Cell Fate Specification Blood Vessel Lumenization Auditory Receptor Cell Fate Commitment Regulation Of Cell Adhesion Involved In Heart Morphogenesis D2 Dopamine Receptor Binding Regulation Of Cell Growth By Extracellular Stimulus Regulation Of Opioid Receptor Signaling Pathway Cellular Response To Morphine Club Cell Differentiation Epidermal Cell Fate Specification Pulmonary Valve Development Endothelial Cell Fate Specification Response To Kainic Acid Spine Apparatus 1-phosphatidylinositol-3-kinase Regulator Activity Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Aortic Valve Development Hair Follicle Maturation Endocardium Development Semi-lunar Valve Development Protein Localization To Actin Cytoskeleton Dendritic Spine Head Positive Regulation Of Protein Localization To Cell Cortex Response To L-phenylalanine Derivative Gland Development PH Reduction Positive Regulation Of Transcription Of Notch Receptor Target Male Mating Behavior Gastric Acid Secretion Sebaceous Gland Development Dorsal Aorta Morphogenesis Extrinsic Component Of Postsynaptic Membrane Cellular Response To Peptide Regulation Of Protein Localization To Cell Cortex Atrioventricular Canal Development Peptide Hormone Receptor Binding Cardiac Muscle Cell Myoblast Differentiation Secondary Heart Field Specification Cardiac Left Ventricle Morphogenesis
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