HEXIM1 and RN7SK

Number of citations of the paper that reports this interaction (PMID 15201869)
87

Data Source:
BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology)

		HEXIM1	RN7SK
Gene Name		hexamethylene bis-acetamide inducible 1	RNA, 7SK small nuclear
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding SnRNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Heart Development Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Systolic blood pressure ( 19430483)
Protein-Protein Interactions		9 interactors: CCNT1 CCNT2 CDK9 EGFR ESR1 RELA RN7SK TERF1 TERF2	6 interactors: CCNT1 CDK9 HEXIM1 HMGA1 LARP7 MEPCE
Entrez ID		10614	125050
HPRD ID		09544
Ensembl ID		ENSG00000186834	ENSG00000202198
Uniprot IDs		O94992
PDB IDs		2GD7 3S9G
Enriched GO Terms of Interacting Partners?		Regulation Of DNA Replication Response To Cobalamin Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Cell Cycle Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Telomeric Loop Formation Age-dependent Telomere Shortening Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of DNA Replication Cellular Response To Growth Factor Stimulus Telomere Maintenance Via Telomere Shortening Response To Growth Factor DNA-templated Transcription, Initiation Positive Regulation Of Transcription, DNA-templated Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression DNA-templated Transcription, Elongation Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Replicative Cell Aging Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of DNA Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Nuclear Cell Cycle DNA Replication Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Negative Regulation Of Protein Catabolic Process Negative Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Telomere Maintenance Cellular Response To Estradiol Stimulus Viral Process RNA-dependent DNA Replication Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Cell Cycle Response To Organic Substance Regulation Of Chromosome Organization Cellular Response To Estrogen Stimulus Telomere Maintenance Via Telomere Lengthening	RNA Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Viral Transcription Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Regulation Of Viral Transcription Positive Regulation Of Viral Process Negative Regulation Of Biosynthetic Process Nitrogen Compound Metabolic Process DNA-templated Transcription, Elongation Viral Process SnRNA Modification Replication Fork Arrest Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity DNA-dependent DNA Replication Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Oncogene-induced Cell Senescence Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Viral Process Senescence-associated Heterochromatin Focus Assembly Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Positive Regulation Of Cellular Senescence Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process DNA-templated Transcription, Initiation Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Chromatin Binding Negative Regulation Of Chromatin Silencing Negative Regulation Of Transcription, DNA-templated Establishment Of Integrated Proviral Latency Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process DNA Replication Positive Regulation Of Cell Aging Establishment Of Viral Latency Heterochromatin Assembly Negative Regulation Of Gene Expression
Tagcloud ?		aml besides bisacetamide carry competing elongation focus hdm2 hexamethylene immunodeficiency importantly inducible minute noteworthy npm npmc nucleophosmin p53 partners polymerase prevented regulators tat tefb third transactivation tumorigenesis ubiquitinate ubiquitination
Tagcloud (Difference) ?		aml besides bisacetamide carry competing elongation focus hdm2 hexamethylene immunodeficiency importantly inducible minute noteworthy npm npmc nucleophosmin p53 partners polymerase prevented regulators tat tefb third transactivation tumorigenesis ubiquitinate ubiquitination
Tagcloud (Intersection) ?