P3H3 and KRTAP9-2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		P3H3	KRTAP9-2
Description		prolyl 3-hydroxylase 3	keratin associated protein 9-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Catalytic Complex	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Iron Ion Binding Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Procollagen-proline 3-dioxygenase Activity L-ascorbic Acid Binding Metal Ion Binding Dioxygenase Activity	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Peptidyl-lysine Hydroxylation Collagen Metabolic Process Collagen Biosynthetic Process
Pathways		Collagen biosynthesis and modifying enzymes	Keratinization
Drugs		Ascorbic acid Proline
Diseases
GWAS
Interacting Genes		6 interacting genes: KRT31 KRTAP1-3 KRTAP12-3 KRTAP9-2 TRIM55 TRIM63	146 interacting genes: ADAM12 ADAMTSL4 AGXT AQP1 ARFGAP1 ATG9A AXIN2 C22orf39 CARD10 CATSPER1 CCDC28A CERK CHRD CNNM3 COL8A1 CRCT1 CREB5 CTRC CYP21A2 CYSRT1 DMRT3 DOCK2 FAM76B FBXO34 GATA1 GEMIN4 GLRX3 GNE GNG13 GUCD1 HAPLN2 HOXA1 ITGB4 JOSD1 KLHL38 KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-3 KRTAP13-1 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP17-1 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-3 KRTAP9-4 KRTAP9-8 LBX1 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LINGO1 LMNTD2 LNX1 LYVE1 MAPKBP1 MEOX2 MGAT5B NBPF19 NOTCH2NLA NR1D2 NR4A3 NTAQ1 NUFIP2 OTX1 P2RY6 P3H3 PDE9A PHLDA1 PIGS PLLP PLSCR1 POTEB3 POU4F2 PRKAB2 PRKAG1 PTPMT1 RCHY1 RNF31 RNF8 SDC3 SHFL SLC13A5 SLC39A7 SMCP SPATA3 SPATA8 SPRY1 SPRY2 SUMO1P1 TFAP2D TMEM190 TMSB10 TRIM54 TSPAN4 TYRO3 VASN VGLL3 ZDHHC1 ZDHHC17 ZNF20 ZNF575 ZNF696
Entrez ID		10536	83899
HPRD ID		10039	13949
Ensembl ID		ENSG00000110811	ENSG00000239886
Uniprot IDs		Q8IVL6	A0A140TA58 Q9BYQ4
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Glycosylation-dependent Protein Binding Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Protein Retention In ER Lumen Protein Modification By Small Protein Conjugation Hrd1p Ubiquitin Ligase Complex Protein Ubiquitination Diapedesis Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Post-translational Protein Modification Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Muscle Atrophy	Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Protein Binding Hair Cycle Identical Protein Binding Regulation Of Neurotrophin TRK Receptor Signaling Pathway
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