ATG7 and ATG10

Number of citations of the paper that reports this interaction (PMID 12482611)
10

Data Source:
HPRD (two hybrid)

		ATG7	ATG10
Gene Name		autophagy related 7	autophagy related 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Cytoplasm Cytosol Axoneme	Intracellular Cytoplasm
	Molecular Function	Ubiquitin Activating Enzyme Activity Protein Binding Transcription Factor Binding Atg12 Activating Enzyme Activity Atg8 Activating Enzyme Activity Protein Homodimerization Activity	Ligase Activity Atg12 Transferase Activity
	Biological Process	Mitochondrion Degradation Liver Development Cellular Protein Modification Process Protein Lipidation C-terminal Protein Lipidation Cellular Amino Acid Metabolic Process Cellular Response To Nitrogen Starvation Mitochondrion Organization Adult Walking Behavior Cellular Response To Starvation Post-embryonic Development Positive Regulation Of Autophagy Protein Transport Positive Regulation Of Macroautophagy Protein Ubiquitination Cerebellar Purkinje Cell Layer Development Pyramidal Neuron Development Central Nervous System Neuron Axonogenesis Cerebral Cortex Development Protein Catabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Protein Modification Process Protein Modification By Small Protein Conjugation Piecemeal Microautophagy Of Nucleus Negative Stranded Viral RNA Replication Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Late Nucleophagy Positive Regulation Of Protein Catabolic Process Neurological System Process Cardiac Muscle Cell Development Membrane Fusion Positive Regulation Of Mucus Secretion Cellular Response To Hyperoxia Negative Regulation Of Histone H4-K16 Acetylation	Protein Lipidation Autophagy Protein Transport Positive Regulation Of Protein Modification Process Protein Modification By Small Protein Conjugation Autophagy In Response To ER Overload
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: APP ATG10 ATG12 ATG3 EEF1D GABARAP GABARAPL2 IRF2 MAP1LC3A MAP1LC3B	3 interactors: ATG12 ATG5 ATG7
Entrez ID		10533	83734
HPRD ID		12293	16497
Ensembl ID		ENSG00000197548	ENSG00000152348
Uniprot IDs		O95352	Q9H0Y0
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleophagy Mitochondrion Degradation Organelle Disassembly Autophagic Vacuole Assembly Macroautophagy Autophagy Vacuole Organization Cellular Response To Starvation Cellular Response To Nitrogen Starvation Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Mitochondrion Organization Response To Nutrient Levels Response To Extracellular Stimulus Organelle Assembly Membrane Fusion Response To Stress Cellular Response To Stress Cell Communication Catabolic Process Response To External Stimulus Cellular Component Assembly Cellular Response To Stimulus Membrane Organization Response To Stimulus Cellular Metabolic Process Autophagy In Response To ER Overload Organelle Organization Synaptic Growth At Neuromuscular Junction Protein Lipidation Lipoprotein Biosynthetic Process Collateral Sprouting In Absence Of Injury Protein Transport Collateral Sprouting Axon Midline Choice Point Recognition Establishment Of Protein Localization Lipoprotein Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Intracellular Transport Axon Choice Point Recognition Mitochondrial Fragmentation Involved In Apoptotic Process Innate Immune Response Neuron Remodeling ER Overload Response Metabolic Process Protein Localization Apoptotic Process Establishment Of Localization In Cell Programmed Cell Death	Cellular Response To Nitrogen Starvation Nucleophagy C-terminal Protein Lipidation Mitochondrion Degradation Organelle Disassembly Negative Regulation Of Histone H4-K16 Acetylation Negative Regulation Of Histone H4 Acetylation Protein Lipidation Lipoprotein Biosynthetic Process Negative Stranded Viral RNA Replication Cellular Response To Starvation Autophagy Lipoprotein Metabolic Process Response To Starvation Cellular Response To Nutrient Levels Regulation Of Histone H4 Acetylation Positive Regulation Of Mucus Secretion Post-translational Protein Modification Cellular Response To Extracellular Stimulus Regulation Of Mucus Secretion Negative Regulation Of Histone Acetylation Negative Regulation Of Peptidyl-lysine Acetylation Negative Regulation Of Protein Acetylation Viral Genome Replication Mitochondrion Organization Response To Nutrient Levels Response To Extracellular Stimulus Autophagic Vacuole Assembly Regulation Of Histone Acetylation Negative Regulation Of Type I Interferon Production Macroautophagy Cardiac Muscle Cell Development Negative Regulation Of Chromosome Organization Vacuole Organization Cardiac Muscle Cell Differentiation Regulation Of Type I Interferon Production Regulation Of Histone Modification Cardiocyte Differentiation Striated Muscle Cell Development Muscle Cell Development Viral Life Cycle Cardiac Muscle Tissue Development Regulation Of Protein Ubiquitination Regulation Of Chromosome Organization Negative Regulation Of Cytokine Production Late Nucleophagy Piecemeal Microautophagy Of Nucleus Striated Muscle Cell Differentiation Cellular Response To Stress Catabolic Process
Tagcloud ?		a1 annexin autophagosome autophagy baf bafilomycin beclin bioactive classical clear crocin cytometric enhancement g1 g2 gammah2ax hct116 inefficient lc3 mild nonfunctional p62 predicting pretreatment programmed saffron sensor treating wild	anchorage autophagic autophagy colon colony driven embryonic ex fully homeostasis ink4a lysosomal maintaining notably p16 p21 phenomena pluripotent restored senescence ser15 sox2 states stem stemness suppressors treat understood vacuole
Tagcloud (Difference) ?		a1 annexin autophagosome baf bafilomycin beclin bioactive classical clear crocin cytometric enhancement g1 g2 gammah2ax hct116 inefficient lc3 mild nonfunctional p62 predicting pretreatment programmed saffron sensor treating wild	anchorage autophagic colon colony driven embryonic ex fully homeostasis ink4a lysosomal maintaining notably p16 p21 phenomena pluripotent restored senescence ser15 sox2 states stem stemness suppressors treat understood vacuole
Tagcloud (Intersection) ?		autophagy