ATG7 and ATG3

Number of citations of the paper that reports this interaction (PubMedID 11825910)
0

Data Source:
HPRD (in vivo)

		ATG7	ATG3
Description		autophagy related 7	autophagy related 3
Image		No pdb structure
GO Annotations	Cellular Component	Phagophore Assembly Site Extracellular Region Cytoplasm Cytosol Axoneme Secretory Granule Lumen Ficolin-1-rich Granule Lumen	Phagophore Assembly Site Cytoplasm Cytosol Atg12-Atg5-Atg16 Complex
	Molecular Function	Protein Binding Ubiquitin-like Modifier Activating Enzyme Activity Atg12 Activating Enzyme Activity Atg8 Activating Enzyme Activity Protein Homodimerization Activity	Protein Binding Transferase Activity Atg8-family Ligase Activity Atg12 Transferase Activity Ubiquitin-like Protein Transferase Activity Enzyme Binding Atg8-family Conjugating Enzyme Activity
	Biological Process	Autophagosome Assembly Mitophagy Protein Lipidation Autophagy Cellular Response To Nitrogen Starvation Cellular Response To Starvation Positive Regulation Of Catabolic Process Protein Transport Macroautophagy Positive Regulation Of Protein Modification Process Response To Nutrient Levels Protein Modification By Small Protein Conjugation Cellular Response To Stress Piecemeal Microautophagy Of The Nucleus Regulation Of Circadian Rhythm Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Protein Catabolic Process Rhythmic Process Defense Response To Virus Regulation Of Macromolecule Metabolic Process Cellular Response To Hyperoxia Regulation Of Primary Metabolic Process	Autophagosome Assembly Autophagy Of Mitochondrion Protein Targeting To Membrane Autophagy Protein Transport Macroautophagy Protein Ubiquitination Mitochondrial Fragmentation Involved In Apoptotic Process Nucleophagy Negative Regulation Of Phagocytosis Glycophagy Regulation Of Cilium Assembly
Pathways		Macroautophagy Macroautophagy Neutrophil degranulation Signaling by BRAF and RAF1 fusions Antigen processing: Ubiquitination & Proteasome degradation	Macroautophagy
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Body fat mass ( 28552196) Body size at age 10 ( 32376654) Circulating chemerin levels ( 25521368) HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899) Heel bone mineral density ( 28869591) Heel bone mineral density x serum urate levels interaction ( 34046847) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Male-pattern baldness ( 28196072) Pulse pressure ( 30578418) Relative hand skill in reading disability ( 24068947) Small vessel stroke ( 29123153) Systolic blood pressure ( 30578418 27618452 27618447) Waist-to-hip ratio adjusted for BMI ( 34021172)	Asthma (childhood onset) ( 23829686)
Interacting Genes		11 interacting genes: APP ATG10 ATG12 ATG3 EEF1D GABARAP GABARAPL2 IRF2 MAP1LC3A MAP1LC3B TRIM7	6 interacting genes: ATG12 ATG7 GABARAP GABARAPL2 MAP1LC3B MOB2
Entrez ID		10533	64422
HPRD ID		12293	10654
Ensembl ID		ENSG00000197548	ENSG00000144848
Uniprot IDs		B3KQM6 O95352	Q9NT62
PDB IDs			4NAW 8AFI 8FKM
Enriched GO Terms of Interacting Partners?		Autophagy Of Mitochondrion Autophagosome Assembly Autophagosome Organization Macroautophagy Vacuole Organization Cellular Response To Nitrogen Starvation Autophagosome Maturation Phosphatidylethanolamine Binding Autophagosome Membrane Autophagy Mitophagy Autophagosome Protein-containing Complex Disassembly Organelle Assembly Atg12 Transferase Activity Phospholipid Binding Atg8-family Ligase Activity Cellular Response To Starvation Atg12-Atg5-Atg16 Complex Response To Stress Response To Starvation Microtubule Binding Cellular Response To Nutrient Levels Cellular Component Assembly Glycophagy Ubiquitin Protein Ligase Binding Catabolic Process GABA Receptor Binding Response To Lead Ion Ubiquitin-like Protein Transferase Activity Cytosol Glycogen Catabolic Process Cellular Response To Copper Ion Nucleophagy Protein-containing Complex Organization Cytoplasmic Vesicle Polysaccharide Catabolic Process Cellular Response To Stress Response To Nutrient Levels Response To Copper Ion Organelle Organization Beta-tubulin Binding Organelle Membrane Endomembrane System Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Atg8-family Conjugating Enzyme Activity	Cellular Response To Nitrogen Starvation Autophagy Of Mitochondrion Autophagosome Assembly Autophagosome Organization Macroautophagy Vacuole Organization Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagosome Autophagy Phosphatidylethanolamine Binding Protein-containing Complex Disassembly Cellular Response To Starvation Response To Starvation Organelle Assembly Cellular Response To Nutrient Levels Axoneme Phospholipid Binding Response To Nutrient Levels GABA Receptor Binding Piecemeal Microautophagy Of The Nucleus Microautophagy Nucleophagy Microtubule Binding Beta-tubulin Binding Catabolic Process Ubiquitin Protein Ligase Binding Regulation Of Protein Catabolic Process Cellular Component Assembly Atg8 Activating Enzyme Activity Atg12 Activating Enzyme Activity Organelle Organization Protein-containing Complex Organization Positive Regulation Of Viral Translation Cellular Response To Stress Cytosol Atg8-family Ligase Activity Positive Regulation Of Protein K48-linked Ubiquitination Cellular Response To Hyperoxia Atg12-Atg5-Atg16 Complex Regulation Of Protein K48-linked Ubiquitination Regulation Of Proteasomal Protein Catabolic Process Cytoplasmic Vesicle Positive Regulation Of Protein Catabolic Process Ceramide Binding Endomembrane System Ubiquitin-like Modifier Activating Enzyme Activity Glycophagy Protein Transport
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