PIBF1 and LMNB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PIBF1	LMNB2
Description		progesterone immunomodulatory binding factor 1	lamin B2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Centrosome Microtubule Organizing Center Cytoskeleton Centriolar Satellite Ciliary Basal Body	Nucleus Nuclear Envelope Nuclear Lamina Intermediate Filament Nuclear Membrane
	Molecular Function	Interleukin-4 Receptor Binding Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding Identical Protein Binding
	Biological Process	Immune System Process Mitotic Metaphase Chromosome Alignment Negative Regulation Of Prostaglandin Biosynthetic Process Negative Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-10 Production Negative Regulation Of Natural Killer Cell Activation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein Activation Of Janus Kinase Activity Cilium Assembly Protein Localization To Centrosome Mitotic Spindle Assembly Non-motile Cilium Assembly	Nuclear Envelope Organization Cytoskeleton Organization Nuclear Migration Heterochromatin Formation Nuclear Pore Localization Protein Localization To Nuclear Envelope
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Blood pressure measurement (low sodium intervention) ( 24165912) Gout ( 32238385) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494) Waist circumference ( 28552196)
Interacting Genes		104 interacting genes: ALAS1 AMOTL2 ANKRD23 ANKRD28 APP ARHGAP45 ARID5A C7orf57 CARD10 CARD9 CATSPERT CBX8 CCDC13 CCDC136 CCDC138 CCHCR1 CDC37 CDK18 CEP135 CEP19 CEP63 CEP70 CFAP53 CWF19L2 DAXX DISC1 DMAP1 EFHC2 ENKD1 FAM161A FAM50B GMCL1 GOLGA2 GPKOW GRIPAP1 HAUS1 HOMEZ IGFN1 KANK2 KATNBL1 KIF9 KIFC3 KLHL2 LARP1B LMNB2 LZTS1 MAD1L1 MAP3K2 MCRS1 MDFI MFAP1 MORF4L1 MORF4L2 MTUS2 NEBL PHF1 PICK1 PKP2 PLEKHA7 POLDIP3 POU6F2 PPP1R18 PRPF18 PTPN21 RAB11FIP2 RBM11 RBM48 RNF151 RNF169 RSPH14 SCNM1 SLU7 SORBS3 SPATA18 STEEP1 SYT17 TAX1BP1 TCEA2 TFIP11 TNFAIP3 TNIP1 TNIP3 TP53BP2 TRAF2 TRAF5 TRIM27 TSGA10 TSHZ2 TSHZ3 UNC45A USP15 USP2 UTP14C XIAP ZBTB16 ZBTB4 ZC2HC1C ZFC3H1 ZFHX3 ZNF250 ZNF35 ZNF438 ZNF620 ZNF774	28 interacting genes: AMOT AMOTL2 CA8 CCDC120 CCDC88B CDC37 EFHC2 FH GOLGA2 LZTS1 MFAP1 MID2 OVOL1 PIBF1 POU6F2 PPP1R13B PRKCD SVIL TFIP11 THAP1 TMPO TP53BP2 TRIM27 TSGA10IP USP2 WASHC3 ZC2HC1C ZFHX3
Entrez ID		10464	84823
HPRD ID		06337	01037
Ensembl ID		ENSG00000083535	ENSG00000176619
Uniprot IDs		Q8WXW3	Q03252
PDB IDs			2LLL
Enriched GO Terms of Interacting Partners?		Protein Binding Identical Protein Binding Centrosome Cytoskeleton Nucleoplasm Spindle Pole Cytoplasm Centriole Regulation Of Innate Immune Response Regulation Of Canonical NF-kappaB Signal Transduction Nucleus Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signaling Pathway Positive Regulation Of Innate Immune Response Negative Regulation Of Nucleobase-containing Compound Metabolic Process Microtubule-based Process Zonula Adherens Maintenance Spliceosomal Complex Microtubule Binding Zinc Ion Binding Regulation Of Primary Metabolic Process Activation Of Innate Immune Response Regulation Of RNA Metabolic Process RNA Splicing CBM Complex Negative Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Defense Response Cell Projection Adherens Junction Maintenance Regulation Of DNA Repair NuA4 Histone Acetyltransferase Complex Regulation Of Immune Response Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway	Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Regulation Of Actin Filament Organization Cytoplasm Regulation Of Autophagy Regulation Of Actin Cytoskeleton Organization Regulation Of Supramolecular Fiber Organization Regulation Of Actin Filament-based Process Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription
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