OLFM1 and TRAF3IP1

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		OLFM1	TRAF3IP1
Gene Name		olfactomedin 1	TNF receptor-associated factor 3 interacting protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cell Junction Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Selective Glutamate Receptor Complex Synapse	Centrosome Cilium Axoneme Intraciliary Transport Particle B Ciliary Basal Body Primary Cilium Ciliary Tip
	Molecular Function	Beta-amyloid Binding Protein Binding	Protein Binding Microtubule Binding
	Biological Process	Nervous System Development Protein Oligomerization Negative Regulation Of Beta-amyloid Formation Negative Regulation Of Neuron Migration	Organelle Organization Neural Tube Patterning Embryonic Camera-type Eye Development Negative Regulation Of Interferon-beta Production Embryonic Heart Tube Development Post-anal Tail Morphogenesis Intraciliary Transport Cilium Assembly Embryonic Digit Morphogenesis Negative Regulation Of Defense Response To Virus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Pathways			Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Response to hepatitis C treatment ( 22095909)	Iris characteristics ( 21835309)
Protein-Protein Interactions		4 interactors: APP DISC1 EGFR TRAF3IP1	27 interactors: ABI2 APP CCDC93 CCNA2 CDC5L DISC1 DMD DST DTNBP1 EXOC1 FRMD4A GOLGA4 IL13RA1 IMMT MACF1 OLFM1 SFR1 SMC2 SMC3 SMC4 SNAP91 SPTBN1 TAB2 TRAF3 TRAF6 TRAK1 WAC
Entrez ID		10439	26146
HPRD ID		09249	09571
Ensembl ID		ENSG00000130558	ENSG00000204104
Uniprot IDs		Q6IMJ7 Q6IMJ8 Q99784	Q8TDR0
PDB IDs			2EQO
Enriched GO Terms of Interacting Partners?		Movement Of Cell Or Subcellular Component Forebrain Development Metal Ion Homeostasis Ion Homeostasis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Cerebral Cortex Cell Migration Regulation Of Synapse Structure Or Activity Nervous System Development Telencephalon Cell Migration Forebrain Cell Migration Cellular Localization Brain Development Microtubule-based Process Head Development Alkanesulfonate Metabolic Process Cell Projection Morphogenesis Microtubule-based Transport Chemical Homeostasis Cell Part Morphogenesis Regulation Of Signal Transduction Cytoskeleton-dependent Intracellular Transport Cerebral Cortex Development Organ Development Central Nervous System Development Regulation Of Signaling Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Synaptic Growth At Neuromuscular Junction Astrocyte Activation Cell Morphogenesis Positive Regulation Of Cellular Protein Metabolic Process Pallium Development Cell Projection Organization Regulation Of Peptidyl-tyrosine Phosphorylation Collateral Sprouting In Absence Of Injury Positive Regulation Of Protein Metabolic Process Locomotion Activation Of Phospholipase A2 Activity Learning Or Memory Homeostatic Process Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Phospholipase A2 Activity Positive Regulation Of Cell Cycle Telencephalon Development Cognition Cellular Calcium Ion Homeostasis Positive Regulation Of Proteolysis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Response To Cobalamin	Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Cell Cycle Process Golgi To Plasma Membrane Protein Transport Meiotic Chromosome Condensation Cell Cycle Golgi Vesicle Transport Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Stress Generation Of Neurons TRIF-dependent Toll-like Receptor Signaling Pathway Neurogenesis Organelle Organization MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Signaling Cell Communication Mitotic Sister Chromatid Segregation Cell Division Establishment Of Protein Localization To Plasma Membrane Regulation Of Neurogenesis Toll-like Receptor 4 Signaling Pathway Nervous System Development Negative Regulation Of Cell Cycle Vesicle-mediated Transport Sister Chromatid Segregation Movement Of Cell Or Subcellular Component Cellular Localization Mitochondrial Calcium Ion Homeostasis Regulation Of Cell Differentiation Toll-like Receptor Signaling Pathway Membrane Organization Regulation Of Cell Development Regulation Of Neuron Differentiation Kinetochore Organization Mitotic Nuclear Division Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Protein Metabolic Process Mitotic Chromosome Condensation Pattern Recognition Receptor Signaling Pathway Regulation Of Cell Cycle Innate Immune Response-activating Signal Transduction Cellular Response To Stimulus Response To Stimulus Activation Of Innate Immune Response Signal Transduction Cell Differentiation Protein Localization To Plasma Membrane DNA Damage Checkpoint Regulation Of Neuron Projection Development
Tagcloud ?			13r1 arches chlamydomonas cilia ciliary ciliogenesis cilium connections cytoskeletal disc1 dyf elipsa enlarged evolutionarily hedgehog homologs ift54 localizes microtubules mipt3 patterning pharyngeal polydactyly raises sequestration stat6 tnfr ventral
Tagcloud (Difference) ?			13r1 arches chlamydomonas cilia ciliary ciliogenesis cilium connections cytoskeletal disc1 dyf elipsa enlarged evolutionarily hedgehog homologs ift54 localizes microtubules mipt3 patterning pharyngeal polydactyly raises sequestration stat6 tnfr ventral
Tagcloud (Intersection) ?