CDS1 and CDC25C

Number of citations of the paper that reports this interaction (PMID 10681541)
95

Data Source:
BioGRID (enzymatic study)

		CDS1	CDC25C
Gene Name		CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1	cell division cycle 25C
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Diacylglycerol Cholinephosphotransferase Activity Phosphatidate Cytidylyltransferase Activity	Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding WW Domain Binding
	Biological Process	Phospholipid Metabolic Process CDP-choline Pathway Phosphatidylinositol Biosynthetic Process Signal Transduction Phototransduction CDP-diacylglycerol Biosynthetic Process Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Replication Mitotic Nuclear Division Regulation Of Mitotic Nuclear Division Spermatogenesis Cell Proliferation Viral Process Peptidyl-tyrosine Dephosphorylation Cell Division Regulation Of Cell Cycle
Pathways		Metabolism of lipids and lipoproteins Synthesis of PI Phospholipid metabolism Glycerophospholipid biosynthesis	Cyclin A/B1 associated events during G2/M transition G2/M DNA damage checkpoint G2/M Checkpoints Activation of ATR in response to replication stress Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex G2/M Transition Cell Cycle Checkpoints Mitotic G2-G2/M phases Cyclin B2 mediated events Polo-like kinase mediated events Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: CDC25C	29 interactors: BRSK1 BRSK2 CCNA2 CCNB1 CDK1 CDK2 CDS1 CHEK1 CHEK2 HRAS LCK LZTS1 MAPK1 MAPK14 MAPK3 MAPK9 MARK3 NEDD4 PCNA PIN1 PKN1 PLK1 PLK3 SRC TP53 YWHAB YWHAH YWHAQ YWHAZ
Entrez ID		1040	995
HPRD ID		11944	01146
Ensembl ID		ENSG00000163624	ENSG00000158402
Uniprot IDs		Q92903	P30307
PDB IDs			3BZI 3OP3
Enriched GO Terms of Interacting Partners?			Cellular Response To Stress Cell Cycle Phosphorylation Response To Stress Cell Cycle Checkpoint Apoptotic Process G2/M Transition Of Mitotic Cell Cycle Programmed Cell Death Cell Death Death Protein Phosphorylation Regulation Of Protein Metabolic Process Intracellular Signal Transduction Positive Regulation Of Cellular Metabolic Process DNA Damage Checkpoint Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Metabolic Process Response To Abiotic Stimulus Regulation Of Mitotic Cell Cycle Positive Regulation Of Protein Phosphorylation Regulation Of Intracellular Transport Negative Regulation Of Mitotic Cell Cycle Ras Protein Signal Transduction Phosphate-containing Compound Metabolic Process Positive Regulation Of Protein Metabolic Process Cell Cycle Process Cellular Response To DNA Damage Stimulus Mitotic Cell Cycle Checkpoint Regulation Of Protein Phosphorylation Cellular Response To Stimulus Positive Regulation Of Phosphorylation Mitotic Cell Cycle Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Intrinsic Apoptotic Signaling Pathway Mitotic Cell Cycle Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Signal Transduction Cell Aging Regulation Of Cellular Localization Regulation Of Phosphorylation Regulation Of Cellular Component Organization Apoptotic Signaling Pathway Positive Regulation Of Intracellular Transport Cellular Protein Modification Process
Tagcloud ?		adopt assemble cdp cycling determines dg droplets esters fission fundamental grow kennedy lifestyle machinery organelles packaging phosphatidic recruit reliant resident rewires route specialized sterol sterols stored triacylglycerol triacylglycerols unusual	acetyltransferase acetyltransferases aiding ancient assembled box caf ccaat collagen disrupted facilitating gcn5 heterodimers histocompatibility lipase nf pivotal possess r2 reductase ribonucleotide transactivation transfections ubiquitous y ya yb yc
Tagcloud (Difference) ?		adopt assemble cdp cycling determines dg droplets esters fission fundamental grow kennedy lifestyle machinery organelles packaging phosphatidic recruit reliant resident rewires route specialized sterol sterols stored triacylglycerol triacylglycerols unusual	acetyltransferase acetyltransferases aiding ancient assembled box caf ccaat collagen disrupted facilitating gcn5 heterodimers histocompatibility lipase nf pivotal possess r2 reductase ribonucleotide transactivation transfections ubiquitous y ya yb yc
Tagcloud (Intersection) ?