CDS1 and UBE2J1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CDS1	UBE2J1
Description		CDP-diacylglycerol synthase 1	ubiquitin conjugating enzyme E2 J1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Hrd1p Ubiquitin Ligase Complex Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Diacylglycerol Cholinephosphotransferase Activity Phosphatidate Cytidylyltransferase Activity Protein Binding Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups Nucleotidyltransferase Activity	Nucleotide Binding Protein Binding ATP Binding Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Lipid Metabolic Process CDP-choline Pathway Phosphatidylinositol Biosynthetic Process Signal Transduction Phototransduction Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process Positive Regulation Of Fat Cell Differentiation Lipid Droplet Formation	Protein Polyubiquitination Spermatid Development Regulation Of Macrophage Cytokine Production Protein Ubiquitination Protein N-linked Glycosylation Via Asparagine Regulation Of Tumor Necrosis Factor Production ERAD Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		Synthesis of PI	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872)
Interacting Genes		7 interacting genes: CDC25C FAM209A RETREG3 SLC10A6 SLC13A4 TMEM237 UBE2J1	50 interacting genes: AQP2 AQP6 BIRC2 BRCA1 CD79A CDS1 CLTRN CREB3 CYB561 DIO2 EBP ELOVL4 FAM209A FAM210B FCER1G GKN1 GOLT1A JAGN1 LAPTM5 LRSAM1 LY6G6C LYVE1 MAPKAPK2 MS4A6E PJA2 PLPPR2 PRKN PROKR2 REEP4 RNF2 SEC11C SLC10A6 SLC26A5 SLC33A2 SLC71A2 SYVN1 TLCD4 TM4SF18 TM4SF19 TMEM14B TMEM31 TMEM51 TMX2 TOPORS TRHR TRIM27 TRIM63 UBA1 UBC UBR5
Entrez ID		1040	51465
HPRD ID		11944	15599
Ensembl ID		ENSG00000163624	ENSG00000198833
Uniprot IDs		Q92903	Q9Y385
PDB IDs
Enriched GO Terms of Interacting Partners?		Sodium:sulfate Symporter Activity Symporter Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport	Membrane Ubiquitin-protein Transferase Activity Ubiquitin Protein Ligase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Polyubiquitination Endoplasmic Reticulum Membrane Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Endoplasmic Reticulum Protein Binding Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Modification-dependent Protein Catabolic Process Renal Water Transport Protein K48-linked Ubiquitination Transferase Activity Ubiquitin Ligase Complex Negative Regulation Of Response To Endoplasmic Reticulum Stress Protein K29-linked Ubiquitination Protein Modification Process
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